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Buy Day today: Good (62) Broad market participation · no major macro event
TGTX

TG Therapeutics Inc

Healthcare · Biotechnology · listed since 1995

56.50$ +1.1% vs. previous close Closing price · As of: Sep 17, 2026
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Assessment

Our Rating

A journalistic assessment by our editorial team at the time of the deep dive — it rates the company, not the entry point. Not investment advice and not a solicitation to buy or sell.

Open questions

The business works in principle, but one material question is open. As long as it stays open, our findings do not carry a quality verdict.

Why this colour

The value signal is real — a profitable, growing biotech with a clean balance sheet — but it deceives about the earnings quality: three quarters of the 2025 record profit is a one-time tax bonus, and almost all the revenue hangs on a single drug against Roche and Novartis. The case is a bet on the further commercialization of BRIUMVI and on the pipeline moving up, at a valuation that already prices in a lot, and with a freshly burdened balance sheet. If the operating profit grows into the valuation, the bet can pay off; if growth stalls, a high expectation meets a one-product business. The decision is yours.

What the thesis turns on

Assessment: Opportunities & Risks

TG Therapeutics is the rare profitable biotech in the value scanner: BRIUMVI, an anti-CD20 agent against multiple sclerosis, has driven revenue from $92 million to $606.9 million and pushed the company into the profit zone. But the 2025 record profit is three quarters a one-time tax bonus, about 98 percent of the business hangs on this one product, and the rivals are named Roche and Novartis. Positive equity and full coffers stand against a loan freshly increased to $750 million. Not investment advice.

Product & growth

BRIUMVI is growing impressively: net product revenue from $92.0 million (2023) to $606.9 million (2025), Q1 2026 alone $201.3 million (plus about 68 percent). The rare case of a profitable biotech with a clear product advantage (short infusion) in a growing MS segment.

Earnings quality

The record 2025 net income of $447.2 million consists of only $107.4 million from the business; $339.8 million is a one-time, non-cash tax bonus from the release of the valuation allowance on deferred taxes. The price-to-earnings ratio therefore looks cheaper than the operating result justifies.

Balance sheet & financing

Positive equity ($583.1 million, 31.03.2026), Altman-Z 6.15, about $572.8 million in cash — no distress. At the same time an accumulated deficit of about $1.1 billion, and in March 2026 the loan was increased from $250 million to $750 million (secured by all assets) with a simultaneous share buyback.

Concentration risk & competition

About 98 percent of revenue hangs on a single drug — "our only marketed product". In the MS market BRIUMVI competes with ocrelizumab (Roche, Ocrevus) and ofatumumab (Novartis, Kesimpta), both from significantly larger corporations; on the horizon possible new BTK inhibitors.

Valuation & momentum

Market value about $8.3 billion, P/S about 12, P/B about 15 — ambitious for a one-product business; Weinstein Stage 2, institutional accumulation, about 79 percent price gain over six months and a buy-leaning analyst consensus. Plenty of success is priced in (data as of July 8, 2026).

Worth Noting

Membership in the value scanner "Joel Greenblatt: Magic Formula" (not a warning scanner) was confirmed locally and live on July 14, 2026; TGTX shows up in 27 value, quality and momentum scanners, in no warning scanner.

All earnings and balance-sheet figures come from the verified annual report 10-K for 2025 (filed 27.02.2026) and the quarterly report 10-Q as of 31.03.2026; the 2025 net income contains a one-time income tax benefit of $339.8 million from the release of the valuation allowance on deferred taxes.

Price and valuation figures dated to July 8, 2026 (about $53.60, about 155 million shares); analyses are evergreen, daily prices are not a buy argument.

Stock Watch

This analysis is as of August 26, 2026. Stock Watch will tell you what's changed at TGTX since then.

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Price history

Chart

Interactive price chart (TradingView).

52-week range: 26.90 $ to 59.10 $ · Last price: 56.50 $ (As of: September 17, 2026)

Key figures

Key figures at a glance

Every figure we hold for this stock, grouped by topic. The question mark next to a label explains what the number means.

Basics

Market Cap ?The value of the entire company on the market: share price times total shares outstanding. 8.7$B
Shares Outstanding ?Total number of shares issued. Price times share count gives market cap. 153m
Float ?Share of stock freely tradable on the market — not locked up in the hands of founders, insiders, or major shareholders. 88.4%
Beta ?Volatility versus the overall market: 1 = moves like the market, 2 = twice as much, under 1 = calmer than the market. 1.7

Performance

Perf. 1M ?Price performance over the last month. 43.50%
Perf. 3M ?Price performance over the last 3 months. 75.50%
Perf. 6M ?Price performance over the last 6 months. 79.30%
YTD Performance (%) ?Price performance since the start of the year (Year to Date). 80.90%
52-Week-High Distance ?How far the price sits below its highest point over the last 52 weeks. 0% means the stock is at its year high. -6.5%
Perf. 1Y ?Price performance over the last 12 months. 76.25%
Perf. 3Y ?Price performance over the last 3 years. 456.90%
Perf. 5Y ?Price performance over the last 5 years. 80.53%
Perf. 10Y ?Price performance over the last 10 years. 674.62%
Perf. Since Inception ?Price performance since the first available trading day (05/13/2013) — with a complete history, that is since the IPO. 882.09%

Technical Indicators

MA 38 Days ?Moving average of the last 38 trading days: the smoothed price path. A price above it signals short-term strength. 52.90$
MA 50 Days ?Moving average of the last 50 trading days — the most widely watched medium-term trend line. 53.50$
MA 200 Days ?Moving average of the last 200 trading days — the dividing line between a long-term uptrend and downtrend. 39.90$
RSI (14) ?Relative Strength Index over 14 days, scale 0 to 100: above 70 counts as overbought, below 30 as oversold. A hint on timing, not a verdict on the company. 58.3
Volatility 30 Days ?Price swings over the last 30 trading days, annualized. The higher the value, the more the price fluctuates. 37.7%
Volatility 250 Days ?Price swings over the last 250 trading days (roughly one market year), annualized. 45.4%

Calculated from the price history · as of 09/18/2026

Valuation

P/E ?Price-to-earnings ratio: how many years of profit does the stock cost? The lower, the cheaper the valuation. No earnings means no P/E. 20.3
Forward P/E ?P/E based on expected earnings for the next 12 months instead of past earnings — analysts' bet on the future. 24.6
PEG ?P/E divided by expected earnings growth: puts valuation in relation to growth. Around 1 is considered fair, well above that is pricey. 1.6
P/B ?Price-to-book ratio: market value relative to book equity. 15.2
P/S ?Price-to-sales ratio: market value divided by annual sales. Important for companies that aren't (yet) profitable. 10.9
EV/EBITDA ?Enterprise value including debt (EV) relative to operating profit before depreciation and amortization (EBITDA) — more comparable than P/E because debt counts too. Extreme values arise when EBITDA is near zero. 59.7
Price/FCF ?Market value divided by free cash flow: how many years of freely available cash does the stock cost? More honest than P/E because cash flow is harder to dress up. 498.6

Profitability

Gross Margin ?Gross margin: what's left of sales after only direct production costs are deducted — the product's pricing power. 82.4%
EBIT Margin ?EBIT margin: operating profit as a percentage of sales — the earning power of the core business before interest and taxes. 17.0%
Net Margin ?Net margin: what's left of sales as profit after ALL costs, interest, and taxes. 55.2%
Return on Equity ?Return on equity: how much profit does the company generate per year on shareholders' equity? 112.6%
Return on Assets ?Return on assets: how much profit the company generates from its total assets (equity and debt combined). 7.3%

Balance Sheet & Safety

Equity Ratio ?Equity ratio: equity as a share of total assets. The higher, the more resilient the balance sheet. 38.1%
Debt/Equity ?Leverage ratio: financial debt divided by equity. Under 1 is generally seen as solid; negative values mean negative equity. 1.3
Altman Z″ ?Edward Altman's bankruptcy early-warning score. We use the Z″ variant, built from four balance-sheet ratios — it is designed for service companies and non-manufacturers and uses book value instead of market value. On that scale: below 1.1 = danger zone, 2.6 and up = safe zone, in between a grey area. Because the classic Altman Z is calculated differently, the two numbers are not directly comparable. The formula does not fit banks, insurers, or real-estate stocks. 6.15
Piotroski ?Balance-sheet health check by Joseph Piotroski: 9 yes/no criteria on profit, cash flow, leverage, and efficiency. 7+ is very solid, under 3 is a red flag. 5 out of 9

Growth

Sales Growth Last Quarter ?Sales growth in the most recently reported quarter versus the same quarter a year ago (YoY). 69.60%
EPS Growth Last Quarter ?Growth in earnings per share in the most recently reported quarter versus the same quarter a year ago (YoY). 300.00%
Sales Growth (Year) ?Sales growth in the last fiscal year versus the year before. 87.32%
Forward Sales Growth ?Sales growth analysts expect over the next 12 months — an estimate, not a guarantee. 30.42%
Forward EPS Growth ?Earnings-per-share growth analysts expect over the next 12 months — an estimate, not a guarantee. 87.10%

Dividend

This stock currently pays no dividend.

Quality & Screener

Stage ?Weinstein phases 1 through 4: 1 = basing, 2 = uptrend (the only buy phase), 3 = topping, 4 = downtrend. Measured against the 30-week line. 2
RS Rating ?Relative strength from 1 to 99: an RS of 95 means the stock has outperformed 95% of all stocks. Top 10% 90
EPS Rating ?Earnings growth rating from 1 to 99 versus all stocks — high values mean above-average earnings growth. Top 10% 92
Fundamental Rating ?Our own Fundamental Rating: 0 to 100 points with an A+ to F grade. 50 points is the average across the universe, 100 the best possible score. It scores growth, earnings surprises, analyst estimates, margins, cash flow, and balance-sheet safety — every stock percentile-ranked against all others. Grades: A+ from 95, A from 75, B from 55, C from 45, D from 25, E from 5, F below. B (65 out of 100)

Highlighted are things our editorial team noticed: green = stands out as strong, red = deserves a closer look. No single metric is a verdict on its own — always read it in context.

Comparison

Industry comparison

The stock alongside the largest companies in the same group. The median row is the middle value of the companies shown above — not of the whole industry.

Industry: Biotechnology

Industry comparison
Company Market cap ($B) P/E EV/EBITDA Gross Margin % EBIT Margin % Sales Growth (Year) % Perf. 1Y %
TG Therapeutics Inc TGTX 8.7 20.3 59.7 82.4 17.0 87.3 76.3
Vertex Pharmaceuticals Inc VRTX 130.6 31.3 24.5 55.0 38.1 9.6 33.4
Regeneron Pharmaceuticals Inc REGN 82.0 19.9 13.1 44.5 20.7 1.0 35.5
Moderna Inc MRNA 62.7 4.6 -66.0 -131.1 -39.2 532.3
argenx NV ARGX 61.9 38.1 34.2 59.1 32.0 89.6 30.9
Revolution Medicines Inc RVMD 40.9 -9.7 -174,708.6 0.0 -100.0 338.3
BeiGene, Ltd. ONC 40.0 63.1 34.1 88.9 19.1 40.2 6.4
Alnylam Pharmaceuticals Inc ALNY 32.6 61.8 28.4 79.7 23.0 65.2 -48.1
Royalty Pharma Plc RPRX 32.5 31.8 19.6 95.8 100.3 5.1 68.6
Median of companies shown 40.9 31.8 24.5 59.1 20.7 9.6 35.5

Based on the most recently reported figures. Only stocks from the same trading venue are lined up, so the market caps are counted in one currency. Compare in a chart →

Fiscal years

Annual Figures

Fiscal years from the audited annual reports, oldest first. EBIT is the operating profit before interest and taxes; total assets are everything the company owns.

Revenue, operating income and net income per fiscal year $M

Revenue Operating income Net income

2016 · Revenue: 0 $M 2016 · Operating income: -79 $M 2016 · Net income: -78 $M 2017 · Revenue: 0 $M 2017 · Operating income: -119 $M 2017 · Net income: -118 $M 2018 · Revenue: 0 $M 2018 · Operating income: -174 $M 2018 · Net income: -173 $M 2019 · Revenue: 0 $M 2019 · Operating income: -169 $M 2019 · Net income: -173 $M 2020 · Revenue: 0 $M 2020 · Operating income: -274 $M 2020 · Net income: -279 $M 2021 · Revenue: 7 $M 2021 · Operating income: -345 $M 2021 · Net income: -348 $M 2022 · Revenue: 3 $M 2022 · Operating income: -218 $M 2022 · Net income: -224 $M 2023 · Revenue: 234 $M 2023 · Operating income: 21 $M 2023 · Net income: 13 $M 2024 · Revenue: 329 $M 2024 · Operating income: 42 $M 2024 · Net income: 23 $M 2025 · Revenue: 616 $M 2025 · Operating income: 123 $M 2025 · Net income: 447 $M
2016201720182019202020212022202320242025
Annual Figures
Fiscal Year Revenue ($M) EBIT ($M) Net Income ($M) EPS ($) Operating Cash Flow ($M) Equity ($M) Total Assets ($M)
2016 0 -79 -78 -1.60 -62 36 55
2017 0 -119 -118 -1.91 -94 67 97
2018 0 -174 -173 -2.30 -129 24 84
2019 0 -169 -173 -1.96 -133 39 163
2020 0 -274 -279 -2.42 -215 519 626
2021 7 -345 -348 -2.63 -296 237 380
2022 3 -218 -224 -1.65 -176 59 194
2023 234 21 13 0.09 -31 161 330
2024 329 42 23 0.15 -41 222 578
2025 616 123 447 2.77 -25 648 1,063

Quarters

Quarterly Figures

Each bar is one quarter, the last one is the most recent. Use the switch to step through the individual figures.

Revenue & Profit

Cash Flow

Balance Sheet

Margins

Per Share

Click the chart or tab into it, then use ← and → to step through the periods.

None of the selected stocks reports this metric. Pick another metric or switch between annual and quarterly.

These companies report in different currencies — switch on “Indexed” or pick a margin for a fair comparison.

The figures could not be loaded right now.

Sales Per Quarter ($M)
2024: Q4 · 108.2 $M Q4 2025: Q1 · 120.9 $M Q1 2025: Q2 · 141.1 $M Q2 2025: Q3 · 161.7 $M Q3 2025: Q4 · 192.6 $M Q4 2026: Q1 · 204.9 $M Q1 2026: Q2 · 240.3 $M Q2

Source: fundamental data

Quarterly Figures
Quarter EPS (Earnings Per Share) EPS YoY (%) Sales ($M) Sales YoY (%) Net Margin (%) OCF ($M) FCF ($M)
2024: Q4 0.15 108 146.00 21.60 -26 -26
2025: Q1 0.03 121 90.40 4.20 -29 -29
2025: Q2 0.17 301.90 141 92.10 20.00 7 7
2025: Q3 2.43 9,956.80 162 92.80 241.70 -23 -23
2025: Q4 0.14 -0.70 193 78.00 12.00 20 20
2026: Q1 0.12 297.50 205 69.60 9.70 -18 -18
2026: Q2 0.05 -70.60 240 70.30 3.20 39 39

What Do These Terms Mean?

EPS (Earnings Per Share):
Quarterly profit divided by the total share count — how much of the profit works out to a single share.
YoY (Year over Year):
Change versus the same quarter a year ago — this is how you compare without seasonal distortion (e.g. the holiday shopping season).
Sales:
All revenue for the quarter, before any costs are deducted — the top line of the income statement.
Net Margin:
What percentage of sales is left over as profit in the end. Negative means the company is posting a loss.
OCF (Operating Cash Flow):
The cash that actually flows into the till from the core business during the quarter — harder to dress up than book profit.
FCF (Free Cash Flow):
Operating cash flow minus capital expenditures — the money that's genuinely free to use, say for paying down debt, buybacks, or dividends.

Compare with other stocks →

Screening

Appears in These Scanners

This stock currently matches 32 of our scanner strategies — each hit links to the scanner.

Backtested Scanners

Growth

Quality & Balance Sheet

Breakout & Setup

Momentum & Trend

Research

Risk & Weakness

Only genuine hits from verified scanners count; pure ranking metrics (P/E, P/S, and similar, which just sort the whole universe) don't count as a hit. Scanners marked in red are red-flag signals (risk/short scanners) — appearing there is not a seal of approval. View all scanners

Outlook

Analysts & Price Target

Combined picture of the price targets and recommendations of every analyst covering the stock. Price targets are expectations for the next 12 months, not promises — and they often follow the price rather than predict it.

Consensus Sell 1 = Strong buy … 5 = Strong sell
Analyst Ratings 9
Price Target (average) 69.71$
Distance to price 23.4% The price target sits 23.4% above the current price.

Distribution of Recommendations

Strong Buy 6
Buy 1
Hold 1
Sell 1
Strong Sell 0

Estimates by Fiscal Year

Estimates by Fiscal Year
Fiscal Year EPS Estimate ($) EPS Range ($) Revenue Estimate ($M) Expected Growth Analysts
12/31/2026 0.95 0.70 – 1.32 960 -65.7% 4
12/31/2027 2.97 2.16 – 4.25 1,318 212.1% 6

Average of the analyst estimates for the coming fiscal years. The range shows how far the most optimistic and the most cautious estimate sit apart — the wider it is, the less certain the expectation.

Valuation

What is priced in?

Free cash flow over the past twelve months is negative, which rules out a serious reverse calculation. Any growth rate only makes a negative cash flow more negative; no present value comes out of it. What the price reflects here is therefore not a stream of cash flows, but the expectation that there will be one at all.

A simplified model calculation — not a forecast and not a recommendation.

AI classification

AI Rating

Neutral

Geprüft am 14.07.2026 gegen den Geschäftsbericht (10-K) 2025 (eingereicht 27.02.2026), den Geschäftsbericht 2024 (03.03.2025) sowie die vier jüngsten Quartalsberichte (10-Q) bis zum 31.03.2026. In den ausgewerteten SEC-Filings von TG Therapeutics findet sich kein wesentlicher KI-Bezug: Das Geschäft dreht sich vollständig um B-Zell-Erkrankungen und den anti-CD20-Antikörper BRIUMVI (ublituximab-xiiy) gegen Multiple Sklerose. „Artificial intelligence“ taucht ausschließlich als Risk-Factor-Thema auf — und dort nur in einer spekulativen „may adopt, use or incorporate“-Formulierung (das Unternehmen „könnte“ künftig KI in seine IT-Systeme aufnehmen) plus generischer Regulierungs- und Cybersecurity-Boilerplate (EU AI Act, „AI-washing“). Es gibt keine KI-Umsatzquelle, keinen belegten operativen KI-Einsatz im Geschäftsmodell und kein konkretes KI-Geschäftsrisiko fürs eigene Modell. Nach dem Kriterienkatalog bleibt es damit bei „Neutral“ (dokumentierter Negativ-Befund).

View the full file — quotes, sources, reviewed filings
„We, directly or through our third-party service providers, may adopt, use or incorporate AI technology and capabilities into information technology systems or software to help us operate our business more efficiently than existing industry tools."

Wir könnten — direkt oder über unsere externen Dienstleister — KI-Technologie und -Fähigkeiten in IT-Systeme oder Software aufnehmen, nutzen oder einbinden, um unser Geschäft effizienter zu betreiben als mit bestehenden Branchenwerkzeugen.

10-K · 2026-02-27 · View SEC filing

„TG Therapeutics is a fully integrated, commercial stage, biotechnology company focused on the acquisition, development and commercialization of novel treatments for B-cell diseases."

TG Therapeutics ist ein voll integriertes Biotechnologie-Unternehmen in der kommerziellen Phase, das sich auf die Akquisition, Entwicklung und Vermarktung neuartiger Behandlungen für B-Zell-Erkrankungen konzentriert.

10-K · 2026-02-27 · View SEC filing

Filings Reviewed: 10-Q 2026-05-06 · 10-Q 2025-11-05 · 10-Q 2025-08-08 · 10-Q 2025-05-09 · 10-K 2026-02-27 · 10-K 2025-03-03

Rated on July 14, 2026 · How the Rating Is Built

Growth

Growth Score

Ten checks against the annual reports — each one passed counts a point.

6 of 10 Solid growth
  • Revenue grows by more than 15% a year over three years 504.6%
  • More than 10% revenue growth is expected for the coming year 30.4%
  • Share count grows by less than 3% a year 6.0%
  • Revenue growth plus cash-flow margin add up to at least 40 ("Rule of 40") 83.3%
  • Gross margin at 40% or higher and without meaningful erosion 83.7%
  • Goodwill from acquisitions does not grow faster than revenue 0.0%
  • Net debt below twice EBITDA 0.9 x EBITDA
  • Operating cash flow covers the profits of the last three years -580 m
  • Return on capital at 15% or higher, or up versus two years ago 13.6%
  • Insiders hold at least 10% or are net buyers 7.5%

A criterion without figures counts neither as passed nor as failed; a score is only produced from 7 judgeable criteria upwards. Source: fundamental data. All ten criteria in detail

Quality check

AAQS

5/10

The AAQS (AlleAktien Quality Score) checks 10 quality criteria on growth, profitability, and balance-sheet strength — per the methodology developed and published by AlleAktien, calculated by us from our own fundamental data. A stock counts as a quality stock from 9 out of 10 points. Where a company has a shorter listing history, we calculate over the fiscal years available (at least five).

  • Sales growth 10Y > 5% 152.1%
  • Exp. sales growth 3Y > 5% 46.2%
  • EBIT growth 10Y > 5%
  • Exp. EBIT growth 3Y > 5% 3.5%
  • Net debt < 4x EBIT 1.0x
  • EBIT positive, 10Y straight 3
  • Max. EBIT decline < 50% 0.0%
  • Return on equity > 15% 69.0%
  • ROCE > 15% 13.6%
  • Expected return > 10% 3.2%

View stocks with the full AAQS score · Read the methodology at AlleAktien

Source: fundamental data

Insiders

Insider Transactions

Reportable transactions by officers and major shareholders from SEC Form 4 filings. "Other" includes things like stock grants and option exercises without a buy/sell character.

Insider Transactions
Date Person Role Type Shares Price Value
Sep 10, 2026 Charney Laurence N Director Sell 5,000 54.96 274,800
Aug 7, 2026 Charney Laurence N Director Other 450 0.00
Aug 7, 2026 Charney Laurence N Director Other 500 0.00
Aug 6, 2026 Charney Laurence N Director Other 5,100 0.00

View all insider transactions →

The company

About the Company

TG Therapeutics, Inc. ist ein biopharmazeutisches Unternehmen in der kommerziellen Phase, das sich auf die Akquisition, Entwicklung und Kommerzialisierung neuartiger Behandlungen für B-Zell-vermittelte Erkrankungen in den USA und international konzentriert.

Employees
399
Headquarters
Morrisville, NC
Address
3020 Carrington Mill Blvd., 27560 Morrisville, United States
Phone
212 554 4484
IPO Date
12/14/1995
ISIN
US88322Q1085
Stock Split
100:5625 on 04/30/2012
Stock Split
1:50 on 07/14/2011

Management

Management
Name Title Birth Year
Michael S. Weiss Esq., J.D. Chairman, CEO & President 1966
Sean A. Power CPA CFO, Corporate Secretary & Treasurer 1982
Jenna Bosco Senior Vice President of Corporate Communications
Adam Waldman Chief Commercialization Officer

Executives per the latest required filings; titles kept in their original language. Source: fundamental data.

Filings

Company Filings (8-K)

An 8-K is the filing a US company must use to disclose material events immediately — takeovers, changes at the top, major contracts or payment troubles, for instance. The links open the original document at the US Securities and Exchange Commission (SEC).

  • 08/03/2026 TG THERAPEUTICS, INC. (TGTX): Results of Operations and Financial Condition; Financial Statements and Exhibits SEC ↗

Data as of: September 17, 2026 · Source: fundamental data & SEC filings (annual and quarterly reports, 10-K/10-Q)

Note: pure fact-based analysis, not investment advice and not a solicitation to buy or sell. All figures without guarantee.

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