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A compact market overview — not investment advice. Source: fundamental data & SEC filings (annual and quarterly reports, 10-K/10-Q).
No. Ticker Company Sector Industry Country Market Cap (B) ▼ P/E Price Chg. % Volume
1 VRTX Vertex Pharmaceuticals Inc Healthcare Biotechnology US 133.1 $ 31.94 526.20 $ +0.70% 1,520,380
2 REGN Regeneron Pharmaceuticals Inc Healthcare Biotechnology US 81.9 $ 19.82 788.00 $ -1.00% 696,664
3 MRNA Moderna Inc Healthcare Biotechnology US 78.9 $ — 198.90 $ +2.10% 6,162,508
4 ARGX argenx NV Healthcare Biotechnology US 59.7 $ 36.67 959.50 $ -0.30% 450,933
5 RVMD Revolution Medicines Inc Healthcare Biotechnology US 42.6 $ — 205.00 $ +2.60% 5,302,462
6 ONC BeiGene, Ltd. Healthcare Biotechnology US 40.8 $ 64.44 360.90 $ +0.20% 633,025
7 ALNY Alnylam Pharmaceuticals Inc Healthcare Biotechnology US 34.0 $ 64.42 256.00 $ +2.60% 1,107,523
8 RPRX Royalty Pharma Plc Healthcare Biotechnology US 32.1 $ 31.44 58.20 $ -0.10% 2,363,530
9 INSM Insmed Inc Healthcare Biotechnology US 25.5 $ — 117.80 $ -3.10% 4,410,743
10 ROIV Roivant Sciences Ltd Healthcare Biotechnology US 25.0 $ — 35.80 $ -0.90% 9,663,408
11 BNTX BioNTech SE Healthcare Biotechnology US 24.7 $ — 98.50 $ -0.70% 685,889
12 INCY Incyte Corporation Healthcare Biotechnology US 24.6 $ 18.57 123.90 $ -0.40% 1,810,500
13 GMAB Genmab AS Healthcare Biotechnology US 22.0 $ 27.75 35.30 $ +1.40% 1,582,149
14 ASND Ascendis Pharma AS Healthcare Biotechnology US 14.8 $ 25.96 225.60 $ -2.20% 418,500
15 JAZZ Jazz Pharmaceuticals PLC Healthcare Biotechnology US 14.7 $ 2,002.37 238.00 $ +0.70% 673,082
16 EXEL Exelixis Inc Healthcare Biotechnology US 14.6 $ 20.12 58.20 $ +0.40% 2,145,680
17 HALO Halozyme Therapeutics Inc Healthcare Biotechnology US 13.4 $ 41.32 113.90 $ -1.10% 1,448,576
18 BBIO BridgeBio Pharma Inc Healthcare Biotechnology US 12.8 $ — 65.60 $ -1.10% 2,752,870
19 CORT Corcept Therapeutics Incorporated Healthcare Biotechnology US 12.5 $ 350.26 116.10 $ -2.00% 1,101,068
20 SMMT Summit Therapeutics PLC Healthcare Biotechnology US 12.3 $ — 15.60 $ -4.70% 4,584,109
21 MDGL Madrigal Pharmaceuticals Inc Healthcare Biotechnology US 12.1 $ — 516.60 $ +0.70% 359,992
22 BMRN Biomarin Pharmaceutical Inc Healthcare Biotechnology US 11.5 $ 44.84 60.30 $ -1.80% 1,428,486
23 TECH Bio-Techne Corp Healthcare Biotechnology US 11.3 $ 103.57 72.60 $ +0.10% 2,055,638
24 AXSM Axsome Therapeutics Inc Healthcare Biotechnology US 10.4 $ — 195.10 $ -0.50% 1,305,389
25 KRYS Krystal Biotech Inc Healthcare Biotechnology US 10.3 $ 47.67 345.80 $ +0.20% 329,642
26 APGE Apogee Therapeutics, Inc. Healthcare Biotechnology US 10.1 $ — 135.10 $ 0.00% 4,847,054
27 NUVL Nuvalent Inc Healthcare Biotechnology US 9.8 $ — 124.00 $ 0.00% 1,167,851
28 KYMR Kymera Therapeutics Inc Healthcare Biotechnology US 9.3 $ — 112.00 $ -3.30% 3,856,806
29 ARWR Arrowhead Pharmaceuticals Inc Healthcare Biotechnology US 9.3 $ — 65.90 $ -0.20% 2,124,334
30 PTGX Protagonist Therapeutics Inc Healthcare Biotechnology US 9.1 $ — 141.90 $ +3.30% 1,026,105
31 CAI Caris Life Sciences, Inc. Healthcare Biotechnology US 9.1 $ — 32.00 $ -0.90% 3,639,202
32 CRNX Crinetics Pharmaceuticals Inc Healthcare Biotechnology US 9.0 $ — 85.00 $ 0.00% 1,449,886
33 TGTX TG Therapeutics Inc Healthcare Biotechnology US 8.9 $ 20.63 57.40 $ -0.20% 1,985,301
34 CYTK Cytokinetics Inc Healthcare Biotechnology US 8.7 $ — 64.70 $ -1.50% 2,377,017
35 IBRX Immunitybio Inc Healthcare Biotechnology US 8.7 $ — 8.40 $ -2.30% 9,349,376
36 PCVX Vaxcyte Inc Healthcare Biotechnology US 8.1 $ — 56.20 $ -1.20% 1,989,502
37 ABVX Abivax S.A. Healthcare Biotechnology US 7.9 $ — 91.10 $ -4.00% 723,225
38 PRAX Praxis Precision Medicines Inc Healthcare Biotechnology US 7.8 $ — 280.80 $ -0.40% 859,437
39 SYRE Spyre Therapeutics Inc. Healthcare Biotechnology US 7.7 $ — 85.70 $ -1.60% 1,863,295
40 IONS Ionis Pharmaceuticals Inc Healthcare Biotechnology US 7.4 $ — 44.50 $ +1.60% 2,583,536
41 IMVT Immunovant Inc Healthcare Biotechnology US 6.9 $ — 33.30 $ -2.10% 1,628,618
42 BLTE Belite Bio Inc Healthcare Biotechnology US 6.7 $ — 167.30 $ -1.20% 237,400
43 RYTM Rhythm Pharmaceuticals Inc Healthcare Biotechnology US 6.7 $ — 98.70 $ +0.40% 679,887
44 CGON CG Oncology, Inc. Healthcare Biotechnology US 6.0 $ — 67.20 $ -2.30% 1,326,550
45 SRRK Scholar Rock Holding Corp Healthcare Biotechnology US 5.8 $ — 48.60 $ 0.00% 2,130,568
46 LGND Ligand Pharmaceuticals Incorporated Healthcare Biotechnology US 5.7 $ 40.76 301.50 $ +0.80% 705,829
47 CRSP Crispr Therapeutics AG Healthcare Biotechnology US 5.5 $ — 54.20 $ -2.60% 2,091,161
48 COGT Cogent Biosciences Inc Healthcare Biotechnology US 5.4 $ — 32.30 $ +2.80% 3,280,579
49 TVTX Travere Therapeutics Inc Healthcare Biotechnology US 5.4 $ — 59.40 $ -1.90% 2,687,706
50 MIRM Mirum Pharmaceuticals Inc Healthcare Biotechnology US 5.3 $ — 89.70 $ +0.40% 1,880,548
51 APLS Apellis Pharmaceuticals Inc Healthcare Biotechnology US 5.3 $ 38.35 3.40 $ -0.07% 0
52 ORKA Oruka Therapeutics, Inc. Healthcare Biotechnology US 5.2 $ — 84.50 $ -1.20% 1,800,194
53 PTCT PTC Therapeutics Inc Healthcare Biotechnology US 5.2 $ — 62.70 $ +0.60% 1,898,872
54 MANE Veradermics, Incorporated Healthcare Biotechnology US 4.9 $ — 116.60 $ +0.70% 561,900
55 DNTH Dianthus Therapeutics Inc. Healthcare Biotechnology US 4.8 $ — 88.60 $ -2.40% 1,478,642
56 DFTX Definium Therapeutics, Inc. Healthcare Biotechnology US 4.8 $ — 36.20 $ -1.50% 8,278,700
57 IOVA Iovance Biotherapeutics Inc Healthcare Biotechnology US 4.7 $ — 11.00 $ +1.90% 8,975,197
58 ERAS Erasca Inc Healthcare Biotechnology US 4.6 $ — 14.30 $ -1.90% 5,417,116
59 VKTX Viking Therapeutics Inc Healthcare Biotechnology US 4.2 $ — 35.60 $ -3.20% 4,262,862
60 TNGX Tango Therapeutics Inc Healthcare Biotechnology US 4.1 $ — 24.90 $ +1.20% 4,499,051
61 EWTX Edgewise Therapeutics Inc Healthcare Biotechnology US 4.0 $ — 39.30 $ -4.40% 804,525
62 CELC Celcuity LLC Healthcare Biotechnology US 3.9 $ — 79.50 $ +0.20% 1,419,771
63 ABCL Abcellera Biologics Inc Healthcare Biotechnology US 3.9 $ — 12.70 $ +0.40% 17,223,620
64 CPRX Catalyst Pharmaceuticals Inc Healthcare Biotechnology US 3.9 $ 18.26 31.50 $ 0.00% 1,152,046
65 PBLS Parabilis Medicines, Inc. Healthcare Biotechnology US 3.8 $ — 31.20 $ -3.90% 329,573
66 RLAY Relay Therapeutics Inc Healthcare Biotechnology US 3.8 $ — 17.50 $ -1.50% 4,833,173
67 LEGN Legend Biotech Corp Healthcare Biotechnology US 3.7 $ — 19.10 $ +0.30% 4,229,200
68 XENE Xenon Pharmaceuticals Inc Healthcare Biotechnology US 3.6 $ — 36.90 $ -2.90% 1,103,249
69 IDYA Ideaya Biosciences Inc Healthcare Biotechnology US 3.5 $ — 36.70 $ -0.10% 1,171,369
70 ACAD ACADIA Pharmaceuticals Inc Healthcare Biotechnology US 3.5 $ 9.97 20.70 $ -6.80% 1,491,590
71 ARQT Arcutis Biotherapeutics Inc Healthcare Biotechnology US 3.4 $ — 26.90 $ +2.50% 1,915,451
72 DNLI Denali Therapeutics Inc Healthcare Biotechnology US 3.2 $ — 20.40 $ -0.40% 1,140,093
73 RCUS Arcus Biosciences Inc Healthcare Biotechnology US 3.1 $ — 24.90 $ -0.50% 2,282,643
74 TARS Tarsus Pharmaceuticals Inc Healthcare Biotechnology US 3.1 $ — 75.70 $ -0.40% 501,621
75 ELVN Enliven Therapeutics Inc. Healthcare Biotechnology US 3.0 $ — 44.80 $ -0.90% 2,767,596
76 PGEN Precigen Inc Healthcare Biotechnology US 2.8 $ — 7.80 $ +0.60% 5,316,279
77 MRVI Maravai Lifesciences Holdings Inc Healthcare Biotechnology US 2.8 $ — 7.60 $ -0.70% 6,472,109
78 ATAI AtaiBeckley Inc. Healthcare Biotechnology US 2.7 $ — 7.40 $ 0.00% 6,959,900
79 ZLAB Zai Lab Ltd Healthcare Biotechnology US 2.7 $ — 25.00 $ -1.20% 3,778,183
80 QURE Uniqure NV Healthcare Biotechnology US 2.7 $ — 38.20 $ -0.20% 983,254
81 DYN Dyne Therapeutics Inc Healthcare Biotechnology US 2.6 $ — 16.00 $ -2.90% 1,627,644
82 NAMS NewAmsterdam Pharma Company N.V. Healthcare Biotechnology US 2.6 $ — 22.60 $ -0.70% 2,336,391
83 GPCR Structure Therapeutics Inc. Healthcare Biotechnology US 2.6 $ — 35.90 $ -0.20% 444,139
84 BEAM Beam Therapeutics Inc Healthcare Biotechnology US 2.6 $ — 24.30 $ -1.60% 2,156,435
85 IRON Disc Medicine Inc. Healthcare Biotechnology US 2.5 $ — 65.20 $ -1.80% 927,948
86 CLDX Celldex Therapeutics Inc Healthcare Biotechnology US 2.4 $ — 31.10 $ -1.20% 1,119,758
87 MBX MBX Biosciences, Inc. Healthcare Biotechnology US 2.4 $ — 53.60 $ -3.20% 1,231,952
88 IMNM Immunome Inc Healthcare Biotechnology US 2.4 $ — 21.40 $ -4.20% 2,804,091
89 NRIX Nurix Therapeutics Inc Healthcare Biotechnology US 2.4 $ — 23.00 $ -2.70% 5,325,756
90 HRMY Harmony Biosciences Holdings Healthcare Biotechnology US 2.3 $ 17.22 41.30 $ +0.20% 522,284
91 VERA Vera Therapeutics Inc Healthcare Biotechnology US 2.3 $ — 32.50 $ -2.40% 2,664,613
92 VRDN Viridian Therapeutics Inc Healthcare Biotechnology US 2.3 $ — 20.50 $ -0.90% 1,877,967
93 SLS Sellas Life Sciences Group Inc Healthcare Biotechnology US 2.3 $ — 11.60 $ -3.10% 14,947,456
94 MLYS Mineralys Therapeutics, Inc. Healthcare Biotechnology US 2.3 $ — 25.90 $ -2.70% 919,049
95 PHVS Pharvaris BV Healthcare Biotechnology US 2.3 $ — 32.00 $ -2.90% 477,250
96 ADMA ADMA Biologics Inc Healthcare Biotechnology US 2.2 $ 14.02 9.40 $ -1.50% 3,535,679
97 CAPR Capricor Therapeutics Inc Healthcare Biotechnology US 2.1 $ — 8.40 $ -2.50% 1,015,631
98 OCUL Ocular Therapeutix Inc Healthcare Biotechnology US 2.1 $ — 9.70 $ -1.70% 2,238,665
99 TRVI Trevi Therapeutics Inc Healthcare Biotechnology US 2.1 $ — 14.40 $ -1.80% 3,555,467
100 AUPH Aurinia Pharmaceuticals Inc Healthcare Biotechnology US 2.1 $ 7.79 16.40 $ -0.90% 2,146,915

A compact market overview — not investment advice. Source: fundamental data & SEC filings (annual and quarterly reports, 10-K/10-Q).

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