BioNTech SE
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Assessment
Our Rating
A journalistic assessment by our editorial team at the time of the deep dive — it rates the company, not the entry point. Not investment advice and not a solicitation to buy or sell.
The business works in principle, but one material question is open. As long as it stays open, our findings do not carry a quality verdict.
Why this colour
There is no basis for red: EUR 16,634.2 million in cash and securities, EUR 17,757.5 million of equity, no meaningful financial debt, and no going-concern indication in the interim report for the period ended June 30, 2026 — at this rate of cash burn the runway extends far beyond ten years. But green is out of reach because the decisive operating question is open, and it is a big one: the legacy COVID-19 vaccine business is shrinking faster than planned, annual guidance had to be cut by roughly one fifth on August 4, 2026, and a third of what remains is a contractual payment rather than a product sale. The new business exists as a pipeline, not as revenue. On top of that comes a leadership change in which both founders clear the bridge and one board seat is still unfilled. Yellow here means: solid substance, an unproven business model for the years after the vaccine. The decision is yours.
What the thesis turns on
Assessment: Opportunities & Risks
BioNTech today is a very large savings account with an expensive research laboratory attached. The balance sheet is exceptional — EUR 16,634.2 million in cash and securities, EUR 17,757.5 million of equity, virtually no financial debt (June 30, 2026). The operating business keeps shrinking: EUR 223.7 million of revenue against a EUR 1,352.7 million loss in the first half of 2026, plus annual guidance cut on August 4, 2026, of which EUR 613 million is a contractual payment. Whether 14 pivotal trials turn into a second viable business will be decided by readouts that are still ahead — and, from February 2027, by a board without either founder. Not investment advice.
Balance sheet and liquidity
EUR 16,634.2 million in cash and security investments against EUR 17,757.5 million of equity and EUR 20,342.6 million of total assets (June 30, 2026), with virtually no financial debt. Even at the first-half 2026 rate of cash burn (EUR 410.5 million), that funds many years of research without a capital increase.
Bristol Myers Squibb partnership
For pumitamig, Bristol Myers Squibb paid $1.5 billion upfront, committed $2.0 billion in non-contingent anniversary payments through 2028, and offered up to $7.6 billion in milestones; profits and losses are shared equally (Form 20-F for 2025, Item 4.B).
Current business
Second-quarter 2026 revenue of EUR 105.6 million against EUR 260.8 million a year earlier, and EUR 223.7 million for the first half; a net loss of EUR 1,352.7 million and an operating cash outflow of EUR 410.5 million over the same period (Form 6-K for the period ended June 30, 2026).
Quality of guidance
2026 revenue guidance was cut on August 4, 2026 from EUR 2.0–2.3 to EUR 1.6–1.9 billion; EUR 613 million of that is a Bristol Myers Squibb contractual payment due in the third quarter, not a product sale. Roughly EUR 1.0 to 1.3 billion is left for the actual product business.
Leadership and ownership
Both founders are leaving operational leadership: Guido Oelkers was appointed Chief Executive Officer on August 3, 2026 (taking office by February 1, 2027), and Özlem Türeci moves to a new company of her own, with her successor still unnamed. AT Impf GmbH held 40.3 percent as of December 31, 2025 and, per the annual report, exercises de facto control.
Legacy items and clean-up costs
Up to EUR 450 million of European Commission repayment exposure from CureVac's 2020 contract (Form 20-F for 2025, Item 3.D); plus, in the first half of 2026, EUR 105.0 million of restructuring costs, EUR 96.1 million of impairments on property, plant and equipment (of which EUR 87.0 million on Marburg and Idar-Oberstein) and EUR 126.9 million on intangible assets. Bearable against EUR 16.6 billion of liquidity, but unbudgeted.
Worth Noting
BNTX reached our research list through two announcements within 48 hours: the appointment of a new chief executive on August 3, 2026 and the cut to 2026 revenue guidance on August 4, 2026.
The SEC treats BioNTech as a foreign private issuer: an annual report on Form 20-F instead of a Form 10-K, and interim reports on Form 6-K instead of Form 10-Q. All figures in this analysis come from the annual report for 2025 (filed March 10, 2026), the annual report for 2023 (2021 and 2022 figures) and the interim report for the period ended June 30, 2026 (filed August 4, 2026).
Reporting currency euro, listing currency U.S. dollar: metrics that mix market value with balance sheet figures (Altman Z-score, net current asset value per share, cash per share) are deliberately left blank in our in-house stock scanner. The market value from fundamental data (about $23.3 billion, as of August 12, 2026) was cross-checked against 251,204,366 shares x $89.50 (the documented second-quarter 2026 buyback price); the deviation is about 4 percent.
Not to be confused with CureVac N.V., part of BioNTech since December 2025, nor with Moderna, Inc. (Nasdaq: MRNA), the U.S. competitor using the same technology with a considerably smaller cash pile.
Stock Watch
This analysis is as of August 12, 2026. Stock Watch will tell you what's changed at BNTX since then.
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Price history
Chart
Interactive price chart (TradingView).
Last price: 92.80 $ (As of: August 12, 2026)
Key figures
Key figures at a glance
Every figure we hold for this stock, grouped by topic. The question mark next to a label explains what the number means.
Basics
Performance
Valuation
Profitability
Balance Sheet & Safety
Growth
Dividend
No dividend data is available for this stock yet.
Quality & Screener
Comparison
Industry comparison
The stock alongside the largest companies in the same group. The median row is the middle value of the companies shown above — not of the whole industry.
Industry: Biotechnology
| Company | Market cap ($B) | P/E | EV/EBITDA | Gross Margin % | EBIT Margin % | Sales Growth (Year) % | Perf. 1Y % |
|---|---|---|---|---|---|---|---|
| BioNTech SE BNTX | 23.3 | – | – | – | -806.6 | 0.2 | – |
| Vertex Pharmaceuticals Inc VRTX | 134.0 | 32.2 | 23.3 | 54.4 | 38.1 | 9.6 | 41.4 |
| Regeneron Pharmaceuticals Inc REGN | 82.8 | 19.9 | 12.7 | 44.5 | 20.7 | 1.0 | 46.8 |
| Revolution Medicines Inc RVMD | 42.8 | – | -9.7 | -151,691.8 | 0.0 | -100.0 | 492.4 |
| Royalty Pharma Plc RPRX | 31.9 | 31.3 | 19.7 | 115.0 | 100.3 | 5.1 | 63.1 |
| Alnylam Pharmaceuticals Inc ALNY | 29.4 | 55.1 | 23.0 | 79.7 | 23.0 | 65.2 | -49.2 |
| Insmed Inc INSM | 28.7 | – | -6.0 | 81.8 | -65.5 | 66.7 | 17.4 |
| Roivant Sciences Ltd ROIV | 24.7 | – | 0.7 | -8,159.0 | -14,675.1 | -71.6 | 215.6 |
| Moderna Inc MRNA | 24.0 | – | 4.6 | -66.0 | -131.1 | -39.2 | 137.8 |
| Median of companies shown | 29.4 | 31.7 | 8.7 | 49.4 | 0.0 | 1.0 | 55.0 |
Based on the most recently reported figures. Only stocks from the same trading venue are lined up, so the market caps are counted in one currency. Compare in a chart →
Quarters
Quarterly Figures
Each bar is one quarter, the last one is the most recent. Use the switch to step through the individual figures.
Revenue & Profit
Cash Flow
Balance Sheet
Margins
Per Share
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· Total · per year
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The figures could not be loaded right now.
Source: fundamental data
| Quarter | EPS (Earnings Per Share) | EPS YoY (%) | Sales (€M) | Sales YoY (%) | Net Margin (%) | OCF (€M) | FCF (€M) |
|---|---|---|---|---|---|---|---|
| 2024: Q3 | 0.81 | 20.90 | 1,245 | 39.00 | 15.90 | -688 | -779 |
| 2024: Q4 | 1.08 | -43.20 | 1,190 | -19.50 | 21.80 | -501 | -602 |
| 2025: Q1 | -1.73 | -22.70 | 183 | -2.60 | -227.50 | -822 | -1,472 |
| 2025: Q2 | -1.60 | 52.40 | 261 | 102.60 | -148.20 | 132 | -436 |
| 2025: Q3 | -0.12 | -114.80 | 1,519 | 22.00 | -1.90 | 855 | 811 |
| 2025: Q4 | -0.33 | -130.60 | 899 | -24.50 | -33.60 | 299 | 238 |
| 2026: Q1 | -1.95 | -12.70 | 120 | -34.30 | -450.40 | -428 | -486 |
| 2026: Q2 | -3.03 | -89.40 | 107 | -58.80 | -777.30 | 11 | -45 |
What Do These Terms Mean?
- EPS (Earnings Per Share):
- Quarterly profit divided by the total share count — how much of the profit works out to a single share.
- YoY (Year over Year):
- Change versus the same quarter a year ago — this is how you compare without seasonal distortion (e.g. the holiday shopping season).
- Sales:
- All revenue for the quarter, before any costs are deducted — the top line of the income statement.
- Net Margin:
- What percentage of sales is left over as profit in the end. Negative means the company is posting a loss.
- OCF (Operating Cash Flow):
- The cash that actually flows into the till from the core business during the quarter — harder to dress up than book profit.
- FCF (Free Cash Flow):
- Operating cash flow minus capital expenditures — the money that's genuinely free to use, say for paying down debt, buybacks, or dividends.
Screening
Appears in These Scanners
This stock currently matches 2 of our scanner strategies — each hit links to the scanner.
Risk & Weakness
Only genuine hits from verified scanners count; pure ranking metrics (P/E, P/S, and similar, which just sort the whole universe) don't count as a hit. Scanners marked in red are red-flag signals (risk/short scanners) — appearing there is not a seal of approval. View all scanners
Outlook
Analysts & Price Target
Combined picture of the price targets and recommendations of every analyst covering the stock. Price targets are expectations for the next 12 months, not promises — and they often follow the price rather than predict it.
No price target is available for this stock.
AI classification
AI Rating
BioNTech besitzt seit Juli 2023 die KI-Firma InstaDeep und führt deren externes Geschäft im Jahresbericht als eigene zahlungsmittelgenerierende Einheit („CGU External Business of InstaDeep“) — KI- und Machine-Learning-Dienste sind damit eine belegte Umsatzquelle an Dritte, nicht nur ein internes Werkzeug.
View the full file — quotes, sources, reviewed filings
„Following our acquisition of InstaDeep Ltd., or InstaDeep, we also face competition in the rapidly growing and developing artificial intelligence, or AI, industry."
Nach unserer Übernahme von InstaDeep Ltd. stehen wir zusätzlich im Wettbewerb in der rasch wachsenden und sich entwickelnden Branche der künstlichen Intelligenz (KI).
20-F · 2026-03-10 · View SEC filing
„We face significant competition from other companies with respect to our AI and machine learning services, along with an evolving regulatory landscape."
Bei unseren KI- und Machine-Learning-Diensten stehen wir in starkem Wettbewerb mit anderen Unternehmen, bei zugleich sich wandelndem Regulierungsumfeld.
20-F · 2026-03-10 · View SEC filing
„If demand for the services developed by InstaDeep does not continue, or if we are unable to improve our AI and machine learning technology in a timely, effective and competitive manner, we may not be able realize the expected outcomes from the InstaDeep acquisition."
Falls die Nachfrage nach den von InstaDeep entwickelten Diensten nicht anhält oder wir unsere KI- und Machine-Learning-Technologie nicht rechtzeitig, wirksam und wettbewerbsfähig verbessern können, werden wir die erwarteten Ergebnisse der InstaDeep-Übernahme möglicherweise nicht erreichen.
20-F · 2026-03-10 · View SEC filing
Filings Reviewed: 6-K 2026-08-04 · 6-K 2026-08-04 · 6-K 2026-08-03 · 20-F/A 2026-07-30 · 6-K 2026-05-05 · 20-F 2026-03-10 · 20-F 2025-03-10
Rated on August 12, 2026 · How the Rating Is Built
Insiders
Insider Transactions
Reportable transactions by officers and major shareholders from SEC Form 4 filings. "Other" includes things like stock grants and option exercises without a buy/sell character.
| Date | Person | Role | Type | Shares | Price | Value |
|---|---|---|---|---|---|---|
| Apr 22, 2026 | Sierk Poetting | COO | Sell | 50,000 | 110.56 | 5,528,000 |
The company
About the Company
BioNTech SE, together with its subsidiaries, engages in the development and commercialization of immunotherapies in Germany. The company offers BNT162, an mRNA vaccine for the treatment of SARS-CoV-2 virus. It also develops oncology drugs under Phase III clinical trial, including Gotistobart for metastatic non-small cell lung cancer, Pumitamig for small cell lung cancer and advanced/metastatic triple-negative breast cancer, and Trastuzumab pamirtecan for metastatic breast cancer and epirubicin and cyclophosphamide; and drugs under Phase 2/3 clinical trial, such as BNT113 for human papillomavirus and head and neck squamous cell carcinoma, as well as Pumitamig for metastatic colorectal and non-small cell lung cancer. In addition, the company engages in the development of oncology drugs under Phase II clinical trial comprising BNT116 for advance non-small cell lung cancer, BNT326/YL202 for multiple solid tumors and advanced/metastatic breast cancer, Autogene cevumeran for advance colorectal cancer, and Gotistobart for platinum-resistant ovarian cancer, as well as Pumitamig for glioblastoma, hepatocellular carcinoma, malignant pleural mesothelioma, neuroendocrine neoplasms, and metastatic pancreatic ductal adenocarcinoma. Further, it develops BNT166 which is Phase II clinical trial for mpox virus; and infectious diseases drugs under Phase 1/2 clinical trial, which include BNT162 + BNT161 for SARS-CoV-2 and influenza, BNT164 for tuberculosis, BNT165 for malaria, and BNT166 for mpox. The company was incorporated in 2008 and is headquartered in Mainz, Germany.
- IPO Year
- 2019
Data as of: August 12, 2026 · Source: fundamental data & SEC filings (annual and quarterly reports, 10-K/10-Q)
Note: pure fact-based analysis, not investment advice and not a solicitation to buy or sell. All figures without guarantee.