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A compact market overview — not investment advice. Source: fundamental data & SEC filings (annual and quarterly reports, 10-K/10-Q).
No. Ticker Company Sector Industry Country Market Cap (B) ▼ P/E Price Chg. % Volume
1 VRTX Vertex Pharmaceuticals Inc Healthcare Biotechnology US 130.6 $ 31.34 516.30 $ +0.30% 1,520,380
2 REGN Regeneron Pharmaceuticals Inc Healthcare Biotechnology US 83.3 $ 20.16 801.80 $ -0.30% 696,664
3 MRNA Moderna Inc Healthcare Biotechnology US 72.2 $ 182.10 $ -0.20% 6,162,508
4 ARGX argenx NV Healthcare Biotechnology US 58.8 $ 36.14 945.80 $ -1.90% 450,933
5 ONC BeiGene, Ltd. Healthcare Biotechnology US 41.3 $ 65.17 365.00 $ -0.80% 633,025
6 RVMD Revolution Medicines Inc Healthcare Biotechnology US 39.7 $ 190.70 $ -1.10% 5,302,462
7 ALNY Alnylam Pharmaceuticals Inc Healthcare Biotechnology US 32.7 $ 62.03 246.50 $ -2.00% 1,107,523
8 RPRX Royalty Pharma Plc Healthcare Biotechnology US 31.8 $ 31.17 57.70 $ -1.50% 2,363,530
9 ROIV Roivant Sciences Ltd Healthcare Biotechnology US 25.7 $ 36.80 $ -3.70% 9,663,408
10 INSM Insmed Inc Healthcare Biotechnology US 25.6 $ 118.30 $ -2.10% 4,410,743
11 BNTX BioNTech SE Healthcare Biotechnology US 24.7 $ 98.50 $ -2.40% 685,889
12 INCY Incyte Corporation Healthcare Biotechnology US 24.7 $ 18.68 124.60 $ -1.80% 1,810,500
13 GMAB Genmab AS Healthcare Biotechnology US 21.7 $ 27.36 34.80 $ -1.30% 1,582,149
14 ASND Ascendis Pharma AS Healthcare Biotechnology US 14.6 $ 25.67 223.10 $ -6.10% 418,500
15 JAZZ Jazz Pharmaceuticals PLC Healthcare Biotechnology US 14.5 $ 1,976.29 234.90 $ -2.40% 673,082
16 EXEL Exelixis Inc Healthcare Biotechnology US 14.2 $ 19.60 56.70 $ -2.40% 2,145,680
17 HALO Halozyme Therapeutics Inc Healthcare Biotechnology US 13.2 $ 40.77 112.40 $ -2.30% 1,448,576
18 SMMT Summit Therapeutics PLC Healthcare Biotechnology US 13.0 $ 16.50 $ -3.90% 4,584,109
19 BBIO BridgeBio Pharma Inc Healthcare Biotechnology US 12.9 $ 65.70 $ -5.10% 2,752,870
20 CORT Corcept Therapeutics Incorporated Healthcare Biotechnology US 12.1 $ 340.60 112.90 $ -3.90% 1,101,068
21 MDGL Madrigal Pharmaceuticals Inc Healthcare Biotechnology US 12.0 $ 513.00 $ -1.10% 359,992
22 BMRN Biomarin Pharmaceutical Inc Healthcare Biotechnology US 11.9 $ 46.25 62.20 $ -1.80% 1,428,486
23 TECH Bio-Techne Corp Healthcare Biotechnology US 11.3 $ 103.43 72.50 $ 0.00% 2,055,638
24 AXSM Axsome Therapeutics Inc Healthcare Biotechnology US 10.3 $ 193.50 $ -4.80% 1,305,389
25 KRYS Krystal Biotech Inc Healthcare Biotechnology US 10.2 $ 47.12 341.80 $ -2.60% 329,642
26 APGE Apogee Therapeutics, Inc. Healthcare Biotechnology US 10.1 $ 135.10 $ 0.00% 4,847,054
27 NUVL Nuvalent Inc Healthcare Biotechnology US 9.8 $ 124.00 $ 0.00% 1,167,851
28 KYMR Kymera Therapeutics Inc Healthcare Biotechnology US 9.6 $ 115.50 $ -5.40% 3,856,806
29 ARWR Arrowhead Pharmaceuticals Inc Healthcare Biotechnology US 9.4 $ 67.00 $ -6.80% 2,124,334
30 CRNX Crinetics Pharmaceuticals Inc Healthcare Biotechnology US 9.0 $ 85.00 $ 0.00% 1,449,886
31 CAI Caris Life Sciences, Inc. Healthcare Biotechnology US 9.0 $ 31.70 $ +0.60% 3,639,202
32 PTGX Protagonist Therapeutics Inc Healthcare Biotechnology US 8.9 $ 138.70 $ -4.40% 1,026,105
33 IBRX Immunitybio Inc Healthcare Biotechnology US 8.9 $ 8.60 $ -7.10% 9,349,376
34 CYTK Cytokinetics Inc Healthcare Biotechnology US 8.8 $ 65.80 $ -2.60% 2,377,017
35 TGTX TG Therapeutics Inc Healthcare Biotechnology US 8.6 $ 20.13 56.00 $ -3.60% 1,985,301
36 PCVX Vaxcyte Inc Healthcare Biotechnology US 8.2 $ 56.50 $ -4.30% 1,989,502
37 ABVX Abivax S.A. Healthcare Biotechnology US 8.1 $ 94.10 $ -4.30% 723,225
38 SYRE Spyre Therapeutics Inc. Healthcare Biotechnology US 7.9 $ 88.20 $ -4.10% 1,863,295
39 PRAX Praxis Precision Medicines Inc Healthcare Biotechnology US 7.8 $ 282.10 $ -6.20% 859,437
40 IONS Ionis Pharmaceuticals Inc Healthcare Biotechnology US 7.3 $ 43.90 $ -4.00% 2,583,536
41 IMVT Immunovant Inc Healthcare Biotechnology US 7.2 $ 34.50 $ -7.40% 1,628,618
42 BLTE Belite Bio Inc Healthcare Biotechnology US 6.8 $ 168.70 $ -3.80% 237,400
43 RYTM Rhythm Pharmaceuticals Inc Healthcare Biotechnology US 6.7 $ 98.20 $ -1.00% 679,887
44 CGON CG Oncology, Inc. Healthcare Biotechnology US 6.5 $ 73.40 $ -5.60% 1,326,550
45 SRRK Scholar Rock Holding Corp Healthcare Biotechnology US 6.0 $ 49.90 $ -2.60% 2,130,568
46 CRSP Crispr Therapeutics AG Healthcare Biotechnology US 5.7 $ 55.80 $ -5.50% 2,091,161
47 LGND Ligand Pharmaceuticals Incorporated Healthcare Biotechnology US 5.6 $ 40.34 298.40 $ 0.00% 705,829
48 ORKA Oruka Therapeutics, Inc. Healthcare Biotechnology US 5.6 $ 89.90 $ -4.90% 1,800,194
49 TVTX Travere Therapeutics Inc Healthcare Biotechnology US 5.5 $ 59.80 $ -0.70% 2,687,706
50 COGT Cogent Biosciences Inc Healthcare Biotechnology US 5.3 $ 31.40 $ -3.70% 3,280,579
51 MIRM Mirum Pharmaceuticals Inc Healthcare Biotechnology US 5.3 $ 89.30 $ -2.30% 1,880,548
52 APLS Apellis Pharmaceuticals Inc Healthcare Biotechnology US 5.3 $ 38.35 3.40 $ -0.07% 0
53 PTCT PTC Therapeutics Inc Healthcare Biotechnology US 5.2 $ 62.30 $ -5.50% 1,898,872
54 DNTH Dianthus Therapeutics Inc. Healthcare Biotechnology US 5.1 $ 93.40 $ -5.00% 1,478,642
55 DFTX Definium Therapeutics, Inc. Healthcare Biotechnology US 5.0 $ 37.70 $ -6.60% 8,278,700
56 VKTX Viking Therapeutics Inc Healthcare Biotechnology US 4.9 $ 41.70 $ +2.00% 4,262,862
57 MANE Veradermics, Incorporated Healthcare Biotechnology US 4.8 $ 116.00 $ -1.80% 561,900
58 ERAS Erasca Inc Healthcare Biotechnology US 4.5 $ 13.90 $ -10.30% 5,417,116
59 IOVA Iovance Biotherapeutics Inc Healthcare Biotechnology US 4.4 $ 10.20 $ -4.20% 8,975,197
60 ACAD ACADIA Pharmaceuticals Inc Healthcare Biotechnology US 4.3 $ 12.23 25.40 $ -3.70% 1,491,590
61 EWTX Edgewise Therapeutics Inc Healthcare Biotechnology US 4.2 $ 41.10 $ -7.80% 804,525
62 PBLS Parabilis Medicines, Inc. Healthcare Biotechnology US 4.1 $ 33.30 $ -12.70% 329,573
63 TNGX Tango Therapeutics Inc Healthcare Biotechnology US 4.0 $ 24.50 $ -4.20% 4,499,051
64 CELC Celcuity LLC Healthcare Biotechnology US 4.0 $ 80.00 $ -4.90% 1,419,771
65 RLAY Relay Therapeutics Inc Healthcare Biotechnology US 3.9 $ 18.00 $ -6.80% 4,833,173
66 CPRX Catalyst Pharmaceuticals Inc Healthcare Biotechnology US 3.9 $ 18.26 31.50 $ 0.00% 1,152,046
67 ABCL Abcellera Biologics Inc Healthcare Biotechnology US 3.8 $ 12.30 $ -2.70% 17,223,620
68 IDYA Ideaya Biosciences Inc Healthcare Biotechnology US 3.6 $ 37.50 $ -5.70% 1,171,369
69 LEGN Legend Biotech Corp Healthcare Biotechnology US 3.6 $ 18.50 $ -1.00% 4,229,200
70 XENE Xenon Pharmaceuticals Inc Healthcare Biotechnology US 3.6 $ 36.60 $ -6.50% 1,103,249
71 ARQT Arcutis Biotherapeutics Inc Healthcare Biotechnology US 3.3 $ 26.40 $ -5.00% 1,915,451
72 RCUS Arcus Biosciences Inc Healthcare Biotechnology US 3.3 $ 26.40 $ -1.80% 2,282,643
73 DNLI Denali Therapeutics Inc Healthcare Biotechnology US 3.3 $ 20.50 $ -5.30% 1,140,093
74 ELVN Enliven Therapeutics Inc. Healthcare Biotechnology US 3.1 $ 46.10 $ -4.40% 2,767,596
75 TARS Tarsus Pharmaceuticals Inc Healthcare Biotechnology US 3.1 $ 74.30 $ -3.60% 501,621
76 QURE Uniqure NV Healthcare Biotechnology US 3.0 $ 42.80 $ -5.60% 983,254
77 ZLAB Zai Lab Ltd Healthcare Biotechnology US 2.9 $ 26.50 $ +0.20% 3,778,183
78 ATAI AtaiBeckley Inc. Healthcare Biotechnology US 2.7 $ 7.40 $ 0.00% 6,959,900
79 IMNM Immunome Inc Healthcare Biotechnology US 2.7 $ 24.20 $ -5.90% 2,804,091
80 DYN Dyne Therapeutics Inc Healthcare Biotechnology US 2.7 $ 16.20 $ -5.30% 1,627,644
81 MRVI Maravai Lifesciences Holdings Inc Healthcare Biotechnology US 2.7 $ 7.40 $ -1.20% 6,472,109
82 NAMS NewAmsterdam Pharma Company N.V. Healthcare Biotechnology US 2.7 $ 22.70 $ -2.70% 2,336,391
83 PGEN Precigen Inc Healthcare Biotechnology US 2.6 $ 7.40 $ -5.70% 5,316,279
84 MBX MBX Biosciences, Inc. Healthcare Biotechnology US 2.6 $ 57.90 $ -6.60% 1,231,952
85 BEAM Beam Therapeutics Inc Healthcare Biotechnology US 2.6 $ 24.40 $ -6.00% 2,156,435
86 GPCR Structure Therapeutics Inc. Healthcare Biotechnology US 2.6 $ 36.00 $ -2.60% 444,139
87 IRON Disc Medicine Inc. Healthcare Biotechnology US 2.5 $ 66.10 $ -3.50% 927,948
88 NRIX Nurix Therapeutics Inc Healthcare Biotechnology US 2.4 $ 23.90 $ -7.00% 5,325,756
89 CLDX Celldex Therapeutics Inc Healthcare Biotechnology US 2.4 $ 31.10 $ -7.10% 1,119,758
90 VRDN Viridian Therapeutics Inc Healthcare Biotechnology US 2.4 $ 21.40 $ -3.10% 1,877,967
91 VERA Vera Therapeutics Inc Healthcare Biotechnology US 2.4 $ 33.10 $ -8.90% 2,664,613
92 MLYS Mineralys Therapeutics, Inc. Healthcare Biotechnology US 2.4 $ 26.90 $ -8.50% 919,049
93 PHVS Pharvaris BV Healthcare Biotechnology US 2.3 $ 33.10 $ -6.10% 477,250
94 HRMY Harmony Biosciences Holdings Healthcare Biotechnology US 2.3 $ 16.88 40.50 $ -2.50% 522,284
95 SLS Sellas Life Sciences Group Inc Healthcare Biotechnology US 2.3 $ 11.50 $ -4.20% 14,947,456
96 ADMA ADMA Biologics Inc Healthcare Biotechnology US 2.2 $ 14.47 9.70 $ -1.10% 3,535,679
97 CAPR Capricor Therapeutics Inc Healthcare Biotechnology US 2.2 $ 8.70 $ -7.20% 1,015,631
98 BHVN Biohaven Ltd. Healthcare Biotechnology US 2.2 $ 13.70 $ -7.90% 6,056,036
99 OCUL Ocular Therapeutix Inc Healthcare Biotechnology US 2.2 $ 10.00 $ -4.80% 2,238,665
100 PVLA Palvella Therapeutics, Inc Healthcare Biotechnology US 2.1 $ 149.60 $ -5.40% 271,366

A compact market overview — not investment advice. Source: fundamental data & SEC filings (annual and quarterly reports, 10-K/10-Q).

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