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A compact market overview — not investment advice. Source: fundamental data & SEC filings (annual and quarterly reports, 10-K/10-Q).
No. Ticker Company Sector Industry Country Market Cap (B) ▼ P/E Price Chg. % Volume
1 VRTX Vertex Pharmaceuticals Inc Healthcare Biotechnology US 119.0 $ 28.58 470.70 $ -1.30% 1,520,380
2 REGN Regeneron Pharmaceuticals Inc Healthcare Biotechnology US 78.9 $ 18.93 759.20 $ -0.40% 696,664
3 RVMD Revolution Medicines Inc Healthcare Biotechnology US 38.0 $ 182.50 $ -2.70% 5,302,462
4 RPRX Royalty Pharma Plc Healthcare Biotechnology US 31.5 $ 30.95 57.20 $ -2.20% 2,363,530
5 ALNY Alnylam Pharmaceuticals Inc Healthcare Biotechnology US 29.2 $ 54.88 220.30 $ +7.20% 1,107,523
6 INCY Incyte Corporation Healthcare Biotechnology US 23.5 $ 17.69 118.40 $ -0.90% 1,810,500
7 ROIV Roivant Sciences Ltd Healthcare Biotechnology US 23.3 $ 33.30 $ -1.70% 9,663,408
8 MRNA Moderna Inc Healthcare Biotechnology US 21.9 $ 55.10 $ +0.60% 6,162,508
9 INSM Insmed Inc Healthcare Biotechnology US 21.3 $ 98.50 $ -0.20% 4,410,743
10 BBIO BridgeBio Pharma Inc Healthcare Biotechnology US 15.7 $ 80.00 $ -0.20% 2,752,870
11 JAZZ Jazz Pharmaceuticals PLC Healthcare Biotechnology US 15.5 $ 2,132.07 251.60 $ -0.50% 673,082
12 EXEL Exelixis Inc Healthcare Biotechnology US 13.8 $ 18.78 55.10 $ +3.80% 2,145,680
13 ARWR Arrowhead Pharmaceuticals Inc Healthcare Biotechnology US 12.1 $ 86.00 $ +1.60% 2,124,334
14 CORT Corcept Therapeutics Incorporated Healthcare Biotechnology US 12.1 $ 332.06 112.80 $ -1.50% 1,101,068
15 BMRN Biomarin Pharmaceutical Inc Healthcare Biotechnology US 11.5 $ 44.41 60.00 $ 0.00% 1,428,486
16 MDGL Madrigal Pharmaceuticals Inc Healthcare Biotechnology US 11.3 $ 482.00 $ +3.10% 359,992
17 TECH Bio-Techne Corp Healthcare Biotechnology US 11.2 $ 103.00 72.10 $ +0.10% 2,055,638
18 AXSM Axsome Therapeutics Inc Healthcare Biotechnology US 11.2 $ 211.00 $ -3.20% 1,305,389
19 ABVX Abivax S.A. Healthcare Biotechnology US 10.8 $ 124.80 $ -0.10% 723,225
20 CYTK Cytokinetics Inc Healthcare Biotechnology US 10.3 $ 76.50 $ -0.90% 2,377,017
21 SMMT Summit Therapeutics PLC Healthcare Biotechnology US 10.3 $ 13.00 $ +0.20% 4,584,109
22 APGE Apogee Therapeutics, Inc. Healthcare Biotechnology US 10.1 $ 134.10 $ 0.00% 4,847,054
23 NUVL Nuvalent Inc Healthcare Biotechnology US 9.8 $ 124.00 $ 0.00% 1,167,851
24 HALO Halozyme Therapeutics Inc Healthcare Biotechnology US 9.7 $ 29.80 82.30 $ -0.30% 1,448,576
25 KRYS Krystal Biotech Inc Healthcare Biotechnology US 9.3 $ 42.82 312.60 $ -8.40% 329,642
26 IONS Ionis Pharmaceuticals Inc Healthcare Biotechnology US 9.1 $ 54.50 $ +5.30% 2,583,536
27 CRNX Crinetics Pharmaceuticals Inc Healthcare Biotechnology US 8.8 $ 83.80 $ +0.30% 1,449,886
28 SYRE Spyre Therapeutics Inc. Healthcare Biotechnology US 8.5 $ 94.90 $ -3.50% 1,863,295
29 PTGX Protagonist Therapeutics Inc Healthcare Biotechnology US 8.5 $ 132.30 $ -3.20% 1,026,105
30 PRAX Praxis Precision Medicines Inc Healthcare Biotechnology US 8.5 $ 305.50 $ -0.80% 859,437
31 KYMR Kymera Therapeutics Inc Healthcare Biotechnology US 8.4 $ 100.30 $ -3.00% 3,856,806
32 IMVT Immunovant Inc Healthcare Biotechnology US 8.0 $ 38.50 $ -0.30% 1,628,618
33 PCVX Vaxcyte Inc Healthcare Biotechnology US 7.7 $ 53.50 $ -1.00% 1,989,502
34 IBRX Immunitybio Inc Healthcare Biotechnology US 7.4 $ 7.20 $ -0.30% 9,349,376
35 TGTX TG Therapeutics Inc Healthcare Biotechnology US 7.1 $ 16.82 46.20 $ -11.30% 1,985,301
36 RYTM Rhythm Pharmaceuticals Inc Healthcare Biotechnology US 7.0 $ 102.80 $ +3.60% 679,887
37 COGT Cogent Biosciences Inc Healthcare Biotechnology US 6.6 $ 38.90 $ -0.20% 3,280,579
38 MIRM Mirum Pharmaceuticals Inc Healthcare Biotechnology US 6.2 $ 104.60 $ -1.30% 1,880,548
39 CGON CG Oncology, Inc. Common stock Healthcare Biotechnology US 6.1 $ 69.20 $ -2.90% 1,326,550
40 XENE Xenon Pharmaceuticals Inc Healthcare Biotechnology US 6.0 $ 62.30 $ -0.70% 1,103,249
41 ORKA Oruka Therapeutics, Inc. Healthcare Biotechnology US 5.9 $ 94.80 $ -1.80% 1,800,194
42 ERAS Erasca Inc Healthcare Biotechnology US 5.7 $ 17.80 $ -1.70% 5,417,116
43 PTCT PTC Therapeutics Inc Healthcare Biotechnology US 5.6 $ 68.10 $ +0.20% 1,898,872
44 SRRK Scholar Rock Holding Corp Healthcare Biotechnology US 5.5 $ 45.90 $ -3.10% 2,130,568
45 LGND Ligand Pharmaceuticals Incorporated Healthcare Biotechnology US 5.5 $ 39.01 292.00 $ +1.60% 705,829
46 CRSP Crispr Therapeutics AG Healthcare Biotechnology US 5.0 $ 49.60 $ +3.30% 2,091,161
47 TVTX Travere Therapeutics Inc Healthcare Biotechnology US 5.0 $ 55.00 $ -1.60% 2,687,706
48 CELC Celcuity LLC Healthcare Biotechnology US 4.3 $ 87.70 $ +1.60% 1,419,771
49 ACAD ACADIA Pharmaceuticals Inc Healthcare Biotechnology US 4.3 $ 12.37 25.60 $ -1.00% 1,491,590
50 DYN Dyne Therapeutics Inc Healthcare Biotechnology US 4.2 $ 25.20 $ +0.20% 1,627,644
51 RLAY Relay Therapeutics Inc Healthcare Biotechnology US 4.1 $ 18.80 $ -0.30% 4,833,173
52 ELVN Enliven Therapeutics Inc. Healthcare Biotechnology US 3.9 $ 58.00 $ +5.90% 2,767,596
53 EWTX Edgewise Therapeutics Inc Healthcare Biotechnology US 3.9 $ 38.40 $ -0.10% 804,525
54 CPRX Catalyst Pharmaceuticals Inc Healthcare Biotechnology US 3.9 $ 18.26 31.50 $ 0.00% 1,152,046
55 VKTX Viking Therapeutics Inc Healthcare Biotechnology US 3.8 $ 32.60 $ +2.70% 4,262,862
56 DNLI Denali Therapeutics Inc Healthcare Biotechnology US 3.7 $ 23.20 $ +0.60% 1,140,093
57 RCUS Arcus Biosciences Inc Healthcare Biotechnology US 3.5 $ 27.60 $ -2.00% 2,282,643
58 IDYA Ideaya Biosciences Inc Healthcare Biotechnology US 3.4 $ 35.40 $ -0.30% 1,171,369
59 ARQT Arcutis Biotherapeutics Inc Healthcare Biotechnology US 3.3 $ 25.90 $ -3.40% 1,915,451
60 CLDX Celldex Therapeutics Inc Healthcare Biotechnology US 3.0 $ 37.70 $ -1.00% 1,119,758
61 IRON Disc Medicine Inc. Healthcare Biotechnology US 2.9 $ 76.30 $ -0.90% 927,948
62 MBX MBX Biosciences, Inc. Healthcare Biotechnology US 2.9 $ 64.40 $ -2.30% 1,231,952
63 BEAM Beam Therapeutics Inc Healthcare Biotechnology US 2.7 $ 25.90 $ +1.50% 2,156,435
64 ATAI AtaiBeckley Inc. Healthcare Biotechnology US 2.7 $ 7.20 $ 0.00% 6,959,900
65 TRVI Trevi Therapeutics Inc Healthcare Biotechnology US 2.6 $ 17.90 $ -1.90% 3,555,467
66 IMNM Immunome Inc Healthcare Biotechnology US 2.6 $ 23.00 $ +1.10% 2,804,091
67 TARS Tarsus Pharmaceuticals Inc Healthcare Biotechnology US 2.5 $ 61.30 $ +3.90% 501,621
68 KOD Kodiak Sciences Inc Healthcare Biotechnology US 2.5 $ 39.80 $ -4.20% 1,021,084
69 RARE Ultragenyx Healthcare Biotechnology US 2.5 $ 25.00 $ +0.40% 1,906,372
70 NRIX Nurix Therapeutics Inc Healthcare Biotechnology US 2.4 $ 23.20 $ 0.00% 5,325,756
71 VCEL Vericel Corp Ord Healthcare Biotechnology US 2.4 $ 46.10 $ +0.20% 546,196
72 PGEN Precigen Inc Healthcare Biotechnology US 2.4 $ 6.60 $ +5.40% 5,316,279
73 MRVI Maravai Lifesciences Holdings Inc Healthcare Biotechnology US 2.3 $ 6.40 $ -2.30% 6,472,109
74 VERA Vera Therapeutics Inc Healthcare Biotechnology US 2.3 $ 32.20 $ +0.40% 2,664,613
75 MLYS Mineralys Therapeutics, Inc. Healthcare Biotechnology US 2.3 $ 25.80 $ +1.00% 919,049
76 VRDN Viridian Therapeutics Inc Healthcare Biotechnology US 2.2 $ 19.30 $ +2.10% 1,877,967
77 BHVN Biohaven Ltd. Healthcare Biotechnology US 2.1 $ 13.40 $ -1.00% 6,056,036
78 NUVB Nuvation Bio Inc Healthcare Biotechnology US 2.1 $ 6.20 $ -2.70% 24,825,400
79 HRMY Harmony Biosciences Holdings Healthcare Biotechnology US 2.0 $ 14.92 35.60 $ +1.00% 522,284
80 ZBIO Zenas BioPharma, Inc. Healthcare Biotechnology US 2.0 $ 31.10 $ -1.00% 1,590,410
81 PVLA Palvella Therapeutics, Inc Healthcare Biotechnology US 2.0 $ 140.80 $ +1.30% 271,366
82 ADMA ADMA Biologics Inc Healthcare Biotechnology US 2.0 $ 12.84 8.70 $ +3.30% 3,535,679
83 TYRA Tyra Biosciences Inc Healthcare Biotechnology US 1.9 $ 32.00 $ +0.50% 653,152
84 RAPP Rapport Therapeutics, Inc. Healthcare Biotechnology US 1.9 $ 40.80 $ -0.50% 410,185
85 URGN UroGen Pharma Ltd Healthcare Biotechnology US 1.9 $ 38.60 $ +0.90% 384,900
86 IOVA Iovance Biotherapeutics Inc Healthcare Biotechnology US 1.9 $ 4.30 $ +6.00% 8,975,197
87 STOK Stoke Therapeutics Inc Healthcare Biotechnology US 1.8 $ 29.60 $ +2.40% 888,448
88 AUPH Aurinia Pharmaceuticals Inc Healthcare Biotechnology US 1.8 $ 6.76 14.60 $ -2.10% 2,146,915
89 OCUL Ocular Therapeutix Inc Healthcare Biotechnology US 1.8 $ 8.40 $ +2.80% 2,238,665
90 GENB Generate Biomedicines, Inc. Healthcare Biotechnology US 1.8 $ 14.30 $ +2.40% 321,963
91 AGIO Agios Pharmaceuticals, Inc. Healthcare Biotechnology US 1.8 $ 30.50 $ +1.70% 762,077
92 SNDX Syndax Pharmaceuticals Inc Healthcare Biotechnology US 1.7 $ 19.20 $ +1.00% 1,443,443
93 RXRX Recursion Pharmaceuticals Inc Healthcare Biotechnology US 1.7 $ 3.20 $ +6.00% 15,484,148
94 FTRE Fortrea Holdings Inc. Healthcare Biotechnology US 1.7 $ 18.90 $ -1.20% 1,918,125
95 SRPT Sarepta Therapeutics Inc Healthcare Biotechnology US 1.7 $ 46.05 15.90 $ +6.90% 2,468,059
96 BCAX Bicara Therapeutics Inc. Healthcare Biotechnology US 1.7 $ 25.70 $ -5.00% 1,210,920
97 ZYME Zymeworks Inc. Common Stock Healthcare Biotechnology US 1.6 $ 21.80 $ -0.60% 410,203
98 ANAB AnaptysBio Inc Healthcare Biotechnology US 1.6 $ 53.70 $ +0.60% 295,015
99 NTLA Intellia Therapeutics Inc Healthcare Biotechnology US 1.6 $ 10.80 $ +0.80% 3,373,935
100 INVA Innoviva Inc Healthcare Biotechnology US 1.5 $ 20.80 $ -1.00% 589,771

A compact market overview — not investment advice. Source: fundamental data & SEC filings (annual and quarterly reports, 10-K/10-Q).

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