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A compact market overview — not investment advice. Source: fundamental data & SEC filings (annual and quarterly reports, 10-K/10-Q).
No. Ticker Company Sector Industry Country Market Cap (B) ▼ P/E Price Chg. % Volume
1 VRTX Vertex Pharmaceuticals Inc Healthcare Biotechnology US 133.5 $ 32.03 527.70 $ +0.30% 1,520,380
2 MRNA Moderna Inc Healthcare Biotechnology US 78.3 $ — 197.30 $ -0.80% 6,162,508
3 REGN Regeneron Pharmaceuticals Inc Healthcare Biotechnology US 78.2 $ 18.92 752.30 $ -4.50% 696,664
4 ARGX argenx NV Healthcare Biotechnology US 60.5 $ 37.16 972.30 $ +1.30% 450,933
5 RVMD Revolution Medicines Inc Healthcare Biotechnology US 41.9 $ — 201.70 $ -1.60% 5,302,462
6 ONC BeiGene, Ltd. Healthcare Biotechnology US 41.5 $ 65.53 367.00 $ +1.70% 633,025
7 ALNY Alnylam Pharmaceuticals Inc Healthcare Biotechnology US 33.9 $ 64.27 255.40 $ -0.20% 1,107,523
8 RPRX Royalty Pharma Plc Healthcare Biotechnology US 32.2 $ 31.55 58.40 $ +0.30% 2,363,530
9 ROIV Roivant Sciences Ltd Healthcare Biotechnology US 25.9 $ — 37.00 $ +3.30% 9,663,408
10 INSM Insmed Inc Healthcare Biotechnology US 25.5 $ — 117.70 $ -0.10% 4,410,743
11 BNTX BioNTech SE Healthcare Biotechnology US 24.9 $ — 99.10 $ +0.60% 685,889
12 INCY Incyte Corporation Healthcare Biotechnology US 24.8 $ 18.71 124.80 $ +0.80% 1,810,500
13 GMAB Genmab AS Healthcare Biotechnology US 22.0 $ 27.83 35.40 $ +0.10% 1,582,149
14 ASND Ascendis Pharma AS Healthcare Biotechnology US 15.1 $ 26.48 230.10 $ +2.00% 418,500
15 JAZZ Jazz Pharmaceuticals PLC Healthcare Biotechnology US 14.7 $ 2,004.89 238.30 $ +0.10% 673,082
16 EXEL Exelixis Inc Healthcare Biotechnology US 14.7 $ 20.19 58.40 $ +0.40% 2,145,680
17 HALO Halozyme Therapeutics Inc Healthcare Biotechnology US 13.3 $ 40.95 112.90 $ -0.90% 1,448,576
18 BBIO BridgeBio Pharma Inc Healthcare Biotechnology US 13.0 $ — 66.60 $ +1.60% 2,752,870
19 CORT Corcept Therapeutics Incorporated Healthcare Biotechnology US 12.4 $ 348.75 115.60 $ -0.40% 1,101,068
20 SMMT Summit Therapeutics PLC Healthcare Biotechnology US 12.2 $ — 15.50 $ -0.80% 4,584,109
21 MDGL Madrigal Pharmaceuticals Inc Healthcare Biotechnology US 12.1 $ — 517.00 $ +0.10% 359,992
22 BMRN Biomarin Pharmaceutical Inc Healthcare Biotechnology US 11.4 $ 44.24 59.50 $ -1.30% 1,428,486
23 TECH Bio-Techne Corp Healthcare Biotechnology US 11.3 $ 103.43 72.50 $ -0.10% 2,055,638
24 AXSM Axsome Therapeutics Inc Healthcare Biotechnology US 10.3 $ — 193.90 $ -0.60% 1,305,389
25 APGE Apogee Therapeutics, Inc. Healthcare Biotechnology US 10.1 $ — 135.10 $ 0.00% 4,847,054
26 KRYS Krystal Biotech Inc Healthcare Biotechnology US 10.1 $ 46.47 337.10 $ -2.50% 329,642
27 NUVL Nuvalent Inc Healthcare Biotechnology US 9.8 $ — 124.00 $ 0.00% 1,167,851
28 KYMR Kymera Therapeutics Inc Healthcare Biotechnology US 9.3 $ — 112.00 $ 0.00% 3,856,806
29 ARWR Arrowhead Pharmaceuticals Inc Healthcare Biotechnology US 9.2 $ — 65.50 $ -0.70% 2,124,334
30 PTGX Protagonist Therapeutics Inc Healthcare Biotechnology US 9.1 $ — 142.40 $ +0.40% 1,026,105
31 CAI Caris Life Sciences, Inc. Healthcare Biotechnology US 9.0 $ — 31.80 $ -0.70% 3,639,202
32 CRNX Crinetics Pharmaceuticals Inc Healthcare Biotechnology US 9.0 $ — 85.00 $ 0.00% 1,449,886
33 CYTK Cytokinetics Inc Healthcare Biotechnology US 8.9 $ — 66.20 $ +2.30% 2,377,017
34 IBRX Immunitybio Inc Healthcare Biotechnology US 8.8 $ — 8.50 $ +0.90% 9,349,376
35 TGTX TG Therapeutics Inc Healthcare Biotechnology US 8.7 $ 20.20 56.20 $ -2.20% 1,985,301
36 PCVX Vaxcyte Inc Healthcare Biotechnology US 8.4 $ — 58.30 $ +3.70% 1,989,502
37 ABVX Abivax S.A. Healthcare Biotechnology US 8.4 $ — 96.90 $ +6.40% 723,225
38 PRAX Praxis Precision Medicines Inc Healthcare Biotechnology US 7.9 $ — 285.70 $ +1.70% 859,437
39 SYRE Spyre Therapeutics Inc. Healthcare Biotechnology US 7.7 $ — 85.80 $ +0.10% 1,863,295
40 IONS Ionis Pharmaceuticals Inc Healthcare Biotechnology US 7.6 $ — 45.60 $ +2.40% 2,583,536
41 IMVT Immunovant Inc Healthcare Biotechnology US 7.0 $ — 33.50 $ +0.60% 1,628,618
42 RYTM Rhythm Pharmaceuticals Inc Healthcare Biotechnology US 6.7 $ — 98.60 $ -0.10% 679,887
43 BLTE Belite Bio Inc Healthcare Biotechnology US 6.7 $ — 165.90 $ -0.80% 237,400
44 CGON CG Oncology, Inc. Healthcare Biotechnology US 6.2 $ — 69.60 $ +3.70% 1,326,550
45 LGND Ligand Pharmaceuticals Incorporated Healthcare Biotechnology US 5.9 $ 42.46 314.10 $ +4.20% 705,829
46 SRRK Scholar Rock Holding Corp Healthcare Biotechnology US 5.9 $ — 49.10 $ +1.00% 2,130,568
47 KOD Kodiak Sciences Inc Healthcare Biotechnology US 5.6 $ — 89.90 $ +178.00% 1,021,084
48 TVTX Travere Therapeutics Inc Healthcare Biotechnology US 5.6 $ — 61.60 $ +3.60% 2,687,706
49 CRSP Crispr Therapeutics AG Healthcare Biotechnology US 5.5 $ — 54.10 $ -0.30% 2,091,161
50 PTCT PTC Therapeutics Inc Healthcare Biotechnology US 5.5 $ — 66.00 $ +5.20% 1,898,872
51 COGT Cogent Biosciences Inc Healthcare Biotechnology US 5.4 $ — 31.90 $ -1.40% 3,280,579
52 APLS Apellis Pharmaceuticals Inc Healthcare Biotechnology US 5.3 $ 38.35 3.40 $ -0.07% 0
53 MIRM Mirum Pharmaceuticals Inc Healthcare Biotechnology US 5.2 $ — 88.00 $ -1.90% 1,880,548
54 ORKA Oruka Therapeutics, Inc. Healthcare Biotechnology US 5.2 $ — 84.20 $ -0.30% 1,800,194
55 DFTX Definium Therapeutics, Inc. Healthcare Biotechnology US 5.1 $ — 38.40 $ +6.20% 8,278,700
56 DNTH Dianthus Therapeutics Inc. Healthcare Biotechnology US 4.8 $ — 87.80 $ -0.80% 1,478,642
57 MANE Veradermics, Incorporated Healthcare Biotechnology US 4.8 $ — 115.00 $ -1.30% 561,900
58 IOVA Iovance Biotherapeutics Inc Healthcare Biotechnology US 4.7 $ — 11.00 $ -0.10% 8,975,197
59 ERAS Erasca Inc Healthcare Biotechnology US 4.5 $ — 14.10 $ -0.80% 5,417,116
60 ABCL Abcellera Biologics Inc Healthcare Biotechnology US 4.2 $ — 13.90 $ +9.60% 17,223,620
61 EWTX Edgewise Therapeutics Inc Healthcare Biotechnology US 4.0 $ — 39.80 $ +1.10% 804,525
62 PBLS Parabilis Medicines, Inc. Healthcare Biotechnology US 4.0 $ — 32.60 $ +4.40% 329,573
63 TNGX Tango Therapeutics Inc Healthcare Biotechnology US 4.0 $ — 24.30 $ -2.50% 4,499,051
64 CELC Celcuity LLC Healthcare Biotechnology US 3.9 $ — 79.60 $ +0.20% 1,419,771
65 VKTX Viking Therapeutics Inc Healthcare Biotechnology US 3.9 $ — 33.00 $ -7.10% 4,262,862
66 CPRX Catalyst Pharmaceuticals Inc Healthcare Biotechnology US 3.9 $ 18.26 31.50 $ 0.00% 1,152,046
67 RLAY Relay Therapeutics Inc Healthcare Biotechnology US 3.8 $ — 17.70 $ +1.30% 4,833,173
68 IDYA Ideaya Biosciences Inc Healthcare Biotechnology US 3.7 $ — 38.20 $ +4.20% 1,171,369
69 LEGN Legend Biotech Corp Healthcare Biotechnology US 3.6 $ — 18.60 $ -2.60% 4,229,200
70 XENE Xenon Pharmaceuticals Inc Healthcare Biotechnology US 3.6 $ — 36.70 $ -0.60% 1,103,249
71 ARQT Arcutis Biotherapeutics Inc Healthcare Biotechnology US 3.5 $ — 27.30 $ +1.50% 1,915,451
72 ACAD ACADIA Pharmaceuticals Inc Healthcare Biotechnology US 3.4 $ 9.87 20.50 $ -0.70% 1,491,590
73 DNLI Denali Therapeutics Inc Healthcare Biotechnology US 3.3 $ — 21.00 $ +2.90% 1,140,093
74 TARS Tarsus Pharmaceuticals Inc Healthcare Biotechnology US 3.2 $ — 76.80 $ +1.50% 501,621
75 RCUS Arcus Biosciences Inc Healthcare Biotechnology US 3.1 $ — 25.00 $ +0.20% 2,282,643
76 ELVN Enliven Therapeutics Inc. Healthcare Biotechnology US 3.1 $ — 46.00 $ +2.80% 2,767,596
77 ZLAB Zai Lab Ltd Healthcare Biotechnology US 2.8 $ — 25.70 $ +2.80% 3,778,183
78 PGEN Precigen Inc Healthcare Biotechnology US 2.8 $ — 7.80 $ +0.80% 5,316,279
79 NAMS NewAmsterdam Pharma Company N.V. Healthcare Biotechnology US 2.8 $ — 23.60 $ +4.40% 2,336,391
80 MRVI Maravai Lifesciences Holdings Inc Healthcare Biotechnology US 2.8 $ — 7.60 $ +0.40% 6,472,109
81 ATAI AtaiBeckley Inc. Healthcare Biotechnology US 2.7 $ — 7.40 $ 0.00% 6,959,900
82 QURE Uniqure NV Healthcare Biotechnology US 2.7 $ — 39.10 $ +2.30% 983,254
83 DYN Dyne Therapeutics Inc Healthcare Biotechnology US 2.7 $ — 16.30 $ +1.90% 1,627,644
84 MBX MBX Biosciences, Inc. Healthcare Biotechnology US 2.6 $ — 57.50 $ +7.30% 1,231,952
85 BEAM Beam Therapeutics Inc Healthcare Biotechnology US 2.5 $ — 24.20 $ -0.20% 2,156,435
86 GPCR Structure Therapeutics Inc. Healthcare Biotechnology US 2.5 $ — 35.10 $ -2.40% 444,139
87 IRON Disc Medicine Inc. Healthcare Biotechnology US 2.5 $ — 64.90 $ -0.50% 927,948
88 CLDX Celldex Therapeutics Inc Healthcare Biotechnology US 2.5 $ — 31.50 $ +1.30% 1,119,758
89 IMNM Immunome Inc Healthcare Biotechnology US 2.4 $ — 21.70 $ +1.30% 2,804,091
90 NRIX Nurix Therapeutics Inc Healthcare Biotechnology US 2.4 $ — 23.70 $ +2.90% 5,325,756
91 ADMA ADMA Biologics Inc Healthcare Biotechnology US 2.3 $ 15.06 10.10 $ +7.90% 3,535,679
92 VERA Vera Therapeutics Inc Healthcare Biotechnology US 2.3 $ — 32.50 $ -0.10% 2,664,613
93 VRDN Viridian Therapeutics Inc Healthcare Biotechnology US 2.3 $ — 20.60 $ +0.50% 1,877,967
94 SLS Sellas Life Sciences Group Inc Healthcare Biotechnology US 2.3 $ — 11.60 $ -0.20% 14,947,456
95 HRMY Harmony Biosciences Holdings Healthcare Biotechnology US 2.3 $ 16.68 40.00 $ -3.00% 522,284
96 PHVS Pharvaris BV Healthcare Biotechnology US 2.3 $ — 31.90 $ -0.30% 477,250
97 MLYS Mineralys Therapeutics, Inc. Healthcare Biotechnology US 2.2 $ — 25.60 $ -0.90% 919,049
98 CAPR Capricor Therapeutics Inc Healthcare Biotechnology US 2.2 $ — 8.70 $ +4.20% 1,015,631
99 BHVN Biohaven Ltd. Healthcare Biotechnology US 2.1 $ — 13.30 $ +2.20% 6,056,036
100 TRVI Trevi Therapeutics Inc Healthcare Biotechnology US 2.1 $ — 14.40 $ -0.10% 3,555,467

A compact market overview — not investment advice. Source: fundamental data & SEC filings (annual and quarterly reports, 10-K/10-Q).

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