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A compact market overview — not investment advice. Source: fundamental data & SEC filings (annual and quarterly reports, 10-K/10-Q).
No. Ticker Company Sector Industry Country Market Cap (B) ▼ P/E Price Chg. % Volume
1 VRTX Vertex Pharmaceuticals Inc Healthcare Biotechnology US 132.1 $ 31.71 522.40 $ +1.20% 1,520,380
2 REGN Regeneron Pharmaceuticals Inc Healthcare Biotechnology US 82.7 $ 20.02 796.00 $ -0.70% 696,664
3 MRNA Moderna Inc Healthcare Biotechnology US 77.3 $ — 194.80 $ +7.00% 6,162,508
4 ARGX argenx NV Healthcare Biotechnology US 59.8 $ 36.77 962.20 $ +1.70% 450,933
5 RVMD Revolution Medicines Inc Healthcare Biotechnology US 41.6 $ — 199.90 $ +4.80% 5,302,462
6 ONC BeiGene, Ltd. Healthcare Biotechnology US 40.7 $ 64.28 360.00 $ -1.40% 633,025
7 ALNY Alnylam Pharmaceuticals Inc Healthcare Biotechnology US 33.1 $ 62.81 249.60 $ +1.20% 1,107,523
8 RPRX Royalty Pharma Plc Healthcare Biotechnology US 32.1 $ 31.49 58.30 $ +1.10% 2,363,530
9 INSM Insmed Inc Healthcare Biotechnology US 26.4 $ — 121.60 $ +2.70% 4,410,743
10 ROIV Roivant Sciences Ltd Healthcare Biotechnology US 25.3 $ — 36.10 $ -1.90% 9,663,408
11 BNTX BioNTech SE Healthcare Biotechnology US 24.9 $ — 99.30 $ +0.80% 685,889
12 INCY Incyte Corporation Healthcare Biotechnology US 24.7 $ 18.65 124.40 $ -0.20% 1,810,500
13 GMAB Genmab AS Healthcare Biotechnology US 21.7 $ 27.36 34.80 $ +0.20% 1,582,149
14 ASND Ascendis Pharma AS Healthcare Biotechnology US 15.1 $ 26.54 230.70 $ +3.40% 418,500
15 EXEL Exelixis Inc Healthcare Biotechnology US 14.6 $ 20.05 58.00 $ +2.20% 2,145,680
16 JAZZ Jazz Pharmaceuticals PLC Healthcare Biotechnology US 14.6 $ 1,988.06 236.30 $ +0.60% 673,082
17 HALO Halozyme Therapeutics Inc Healthcare Biotechnology US 13.5 $ 41.79 115.20 $ +2.50% 1,448,576
18 BBIO BridgeBio Pharma Inc Healthcare Biotechnology US 13.0 $ — 66.30 $ +0.90% 2,752,870
19 SMMT Summit Therapeutics PLC Healthcare Biotechnology US 12.9 $ — 16.40 $ -0.40% 4,584,109
20 CORT Corcept Therapeutics Incorporated Healthcare Biotechnology US 12.7 $ 357.50 118.50 $ +4.90% 1,101,068
21 MDGL Madrigal Pharmaceuticals Inc Healthcare Biotechnology US 12.0 $ — 513.20 $ 0.00% 359,992
22 BMRN Biomarin Pharmaceutical Inc Healthcare Biotechnology US 11.7 $ 45.66 61.40 $ -1.40% 1,428,486
23 TECH Bio-Techne Corp Healthcare Biotechnology US 11.3 $ 103.57 72.60 $ +0.10% 2,055,638
24 AXSM Axsome Therapeutics Inc Healthcare Biotechnology US 10.4 $ — 196.00 $ +1.30% 1,305,389
25 KRYS Krystal Biotech Inc Healthcare Biotechnology US 10.3 $ 47.56 345.00 $ +0.90% 329,642
26 APGE Apogee Therapeutics, Inc. Healthcare Biotechnology US 10.1 $ — 135.10 $ 0.00% 4,847,054
27 NUVL Nuvalent Inc Healthcare Biotechnology US 9.8 $ — 124.00 $ 0.00% 1,167,851
28 KYMR Kymera Therapeutics Inc Healthcare Biotechnology US 9.6 $ — 115.80 $ +0.30% 3,856,806
29 ARWR Arrowhead Pharmaceuticals Inc Healthcare Biotechnology US 9.3 $ — 66.10 $ -1.30% 2,124,334
30 CAI Caris Life Sciences, Inc. Healthcare Biotechnology US 9.1 $ — 32.30 $ +2.00% 3,639,202
31 CRNX Crinetics Pharmaceuticals Inc Healthcare Biotechnology US 9.0 $ — 85.00 $ 0.00% 1,449,886
32 IBRX Immunitybio Inc Healthcare Biotechnology US 8.9 $ — 8.60 $ +0.10% 9,349,376
33 TGTX TG Therapeutics Inc Healthcare Biotechnology US 8.9 $ 20.67 57.50 $ +2.70% 1,985,301
34 CYTK Cytokinetics Inc Healthcare Biotechnology US 8.8 $ — 65.70 $ -0.20% 2,377,017
35 PTGX Protagonist Therapeutics Inc Healthcare Biotechnology US 8.8 $ — 137.30 $ -1.00% 1,026,105
36 PCVX Vaxcyte Inc Healthcare Biotechnology US 8.2 $ — 56.90 $ +0.70% 1,989,502
37 ABVX Abivax S.A. Healthcare Biotechnology US 8.2 $ — 94.90 $ +0.80% 723,225
38 SYRE Spyre Therapeutics Inc. Healthcare Biotechnology US 7.8 $ — 87.10 $ -1.20% 1,863,295
39 PRAX Praxis Precision Medicines Inc Healthcare Biotechnology US 7.8 $ — 281.80 $ -0.10% 859,437
40 IONS Ionis Pharmaceuticals Inc Healthcare Biotechnology US 7.3 $ — 43.80 $ -0.30% 2,583,536
41 IMVT Immunovant Inc Healthcare Biotechnology US 7.1 $ — 34.00 $ -1.60% 1,628,618
42 BLTE Belite Bio Inc Healthcare Biotechnology US 6.8 $ — 169.40 $ +0.50% 237,400
43 RYTM Rhythm Pharmaceuticals Inc Healthcare Biotechnology US 6.7 $ — 98.30 $ +0.10% 679,887
44 CGON CG Oncology, Inc. Healthcare Biotechnology US 6.1 $ — 68.80 $ -6.30% 1,326,550
45 SRRK Scholar Rock Holding Corp Healthcare Biotechnology US 5.8 $ — 48.60 $ -2.50% 2,130,568
46 CRSP Crispr Therapeutics AG Healthcare Biotechnology US 5.7 $ — 55.70 $ -0.10% 2,091,161
47 LGND Ligand Pharmaceuticals Incorporated Healthcare Biotechnology US 5.6 $ 40.42 299.00 $ +0.20% 705,829
48 TVTX Travere Therapeutics Inc Healthcare Biotechnology US 5.5 $ — 60.60 $ +1.30% 2,687,706
49 COGT Cogent Biosciences Inc Healthcare Biotechnology US 5.3 $ — 31.40 $ +0.10% 3,280,579
50 MIRM Mirum Pharmaceuticals Inc Healthcare Biotechnology US 5.3 $ — 89.40 $ 0.00% 1,880,548
51 ORKA Oruka Therapeutics, Inc. Healthcare Biotechnology US 5.3 $ — 85.50 $ -4.90% 1,800,194
52 APLS Apellis Pharmaceuticals Inc Healthcare Biotechnology US 5.3 $ 38.35 3.40 $ -0.07% 0
53 PTCT PTC Therapeutics Inc Healthcare Biotechnology US 5.2 $ — 62.30 $ -0.10% 1,898,872
54 DNTH Dianthus Therapeutics Inc. Healthcare Biotechnology US 5.0 $ — 90.70 $ -2.90% 1,478,642
55 DFTX Definium Therapeutics, Inc. Healthcare Biotechnology US 4.9 $ — 36.70 $ -2.40% 8,278,700
56 MANE Veradermics, Incorporated Healthcare Biotechnology US 4.8 $ — 115.70 $ -0.10% 561,900
57 ERAS Erasca Inc Healthcare Biotechnology US 4.6 $ — 14.50 $ +4.10% 5,417,116
58 IOVA Iovance Biotherapeutics Inc Healthcare Biotechnology US 4.6 $ — 10.80 $ +6.00% 8,975,197
59 VKTX Viking Therapeutics Inc Healthcare Biotechnology US 4.3 $ — 36.80 $ -11.80% 4,262,862
60 EWTX Edgewise Therapeutics Inc Healthcare Biotechnology US 4.2 $ — 41.20 $ +0.20% 804,525
61 TNGX Tango Therapeutics Inc Healthcare Biotechnology US 4.0 $ — 24.60 $ +0.70% 4,499,051
62 PBLS Parabilis Medicines, Inc. Healthcare Biotechnology US 4.0 $ — 32.50 $ -2.50% 329,573
63 CELC Celcuity LLC Healthcare Biotechnology US 3.9 $ — 79.40 $ -0.80% 1,419,771
64 ABCL Abcellera Biologics Inc Healthcare Biotechnology US 3.9 $ — 12.70 $ +2.80% 17,223,620
65 CPRX Catalyst Pharmaceuticals Inc Healthcare Biotechnology US 3.9 $ 18.26 31.50 $ 0.00% 1,152,046
66 RLAY Relay Therapeutics Inc Healthcare Biotechnology US 3.8 $ — 17.70 $ -1.70% 4,833,173
67 ACAD ACADIA Pharmaceuticals Inc Healthcare Biotechnology US 3.7 $ 10.69 22.20 $ -12.80% 1,491,590
68 XENE Xenon Pharmaceuticals Inc Healthcare Biotechnology US 3.7 $ — 38.10 $ +4.10% 1,103,249
69 LEGN Legend Biotech Corp Healthcare Biotechnology US 3.7 $ — 19.10 $ +3.30% 4,229,200
70 IDYA Ideaya Biosciences Inc Healthcare Biotechnology US 3.5 $ — 36.70 $ -1.90% 1,171,369
71 ARQT Arcutis Biotherapeutics Inc Healthcare Biotechnology US 3.3 $ — 26.30 $ -0.40% 1,915,451
72 DNLI Denali Therapeutics Inc Healthcare Biotechnology US 3.3 $ — 20.50 $ 0.00% 1,140,093
73 RCUS Arcus Biosciences Inc Healthcare Biotechnology US 3.2 $ — 25.10 $ -5.00% 2,282,643
74 TARS Tarsus Pharmaceuticals Inc Healthcare Biotechnology US 3.1 $ — 76.00 $ +2.20% 501,621
75 ELVN Enliven Therapeutics Inc. Healthcare Biotechnology US 3.1 $ — 45.20 $ -2.00% 2,767,596
76 MRVI Maravai Lifesciences Holdings Inc Healthcare Biotechnology US 2.8 $ — 7.70 $ +3.80% 6,472,109
77 PGEN Precigen Inc Healthcare Biotechnology US 2.7 $ — 7.70 $ +3.50% 5,316,279
78 ATAI AtaiBeckley Inc. Healthcare Biotechnology US 2.7 $ — 7.40 $ 0.00% 6,959,900
79 ZLAB Zai Lab Ltd Healthcare Biotechnology US 2.7 $ — 25.30 $ -4.40% 3,778,183
80 DYN Dyne Therapeutics Inc Healthcare Biotechnology US 2.7 $ — 16.50 $ +1.70% 1,627,644
81 QURE Uniqure NV Healthcare Biotechnology US 2.7 $ — 38.30 $ -10.40% 983,254
82 NAMS NewAmsterdam Pharma Company N.V. Healthcare Biotechnology US 2.7 $ — 22.70 $ +0.30% 2,336,391
83 BEAM Beam Therapeutics Inc Healthcare Biotechnology US 2.6 $ — 24.70 $ +1.20% 2,156,435
84 GPCR Structure Therapeutics Inc. Healthcare Biotechnology US 2.6 $ — 36.00 $ +0.20% 444,139
85 IRON Disc Medicine Inc. Healthcare Biotechnology US 2.6 $ — 66.40 $ +0.50% 927,948
86 IMNM Immunome Inc Healthcare Biotechnology US 2.5 $ — 22.30 $ -7.80% 2,804,091
87 MBX MBX Biosciences, Inc. Healthcare Biotechnology US 2.5 $ — 55.40 $ -4.30% 1,231,952
88 CLDX Celldex Therapeutics Inc Healthcare Biotechnology US 2.5 $ — 31.50 $ +1.20% 1,119,758
89 NRIX Nurix Therapeutics Inc Healthcare Biotechnology US 2.4 $ — 23.70 $ -1.00% 5,325,756
90 VERA Vera Therapeutics Inc Healthcare Biotechnology US 2.4 $ — 33.30 $ +0.90% 2,664,613
91 SLS Sellas Life Sciences Group Inc Healthcare Biotechnology US 2.4 $ — 12.00 $ +4.00% 14,947,456
92 HRMY Harmony Biosciences Holdings Healthcare Biotechnology US 2.3 $ 17.18 41.20 $ +1.70% 522,284
93 VRDN Viridian Therapeutics Inc Healthcare Biotechnology US 2.3 $ — 20.70 $ -3.60% 1,877,967
94 PHVS Pharvaris BV Healthcare Biotechnology US 2.3 $ — 33.00 $ -0.20% 477,250
95 MLYS Mineralys Therapeutics, Inc. Healthcare Biotechnology US 2.3 $ — 26.60 $ -1.10% 919,049
96 ADMA ADMA Biologics Inc Healthcare Biotechnology US 2.2 $ 14.17 9.50 $ -1.90% 3,535,679
97 CAPR Capricor Therapeutics Inc Healthcare Biotechnology US 2.1 $ — 8.60 $ -1.20% 1,015,631
98 TRVI Trevi Therapeutics Inc Healthcare Biotechnology US 2.1 $ — 14.70 $ +1.50% 3,555,467
99 OCUL Ocular Therapeutix Inc Healthcare Biotechnology US 2.1 $ — 9.80 $ -1.80% 2,238,665
100 PVLA Palvella Therapeutics, Inc Healthcare Biotechnology US 2.1 $ — 146.10 $ -2.30% 271,366

A compact market overview — not investment advice. Source: fundamental data & SEC filings (annual and quarterly reports, 10-K/10-Q).

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