AC Immune Ltd
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Price history
Chart
Interactive price chart (TradingView).
52-week range: 2.10 $ to 4.00 $ · Last price: 2.50 $ (As of: September 25, 2026)
Key figures
Key figures at a glance
Every figure we hold for this stock, grouped by topic. The question mark next to a label explains what the number means.
Basics
Performance
Technical Indicators
Calculated from the price history · as of 09/25/2026
Valuation
Profitability
Balance Sheet & Safety
Growth
Dividend
This stock currently pays no dividend.
Quality & Screener
Highlighted are things our editorial team noticed: green = stands out as strong, red = deserves a closer look. No single metric is a verdict on its own — always read it in context.
Comparison
Industry comparison
The stock alongside the largest companies in the same group. The median row is the middle value of the companies shown above — not of the whole industry.
Industry: Biotechnology
| Company | Market cap ($B) | P/E | EV/EBITDA | Gross Margin % | EBIT Margin % | Sales Growth (Year) % | Perf. 1Y % |
|---|---|---|---|---|---|---|---|
| AC Immune Ltd ACIU | 0.3 | – | -0.8 | -162.2 | 7.9 | -86.9 | -2.6 |
| Vertex Pharmaceuticals Inc VRTX | 133.1 | 31.9 | 24.4 | 55.0 | 38.1 | 9.6 | 37.8 |
| Regeneron Pharmaceuticals Inc REGN | 81.9 | 19.8 | 13.5 | 44.5 | 20.7 | 1.0 | 38.7 |
| Moderna Inc MRNA | 78.9 | – | 4.6 | -66.0 | -131.1 | -39.2 | 708.1 |
| argenx NV ARGX | 59.7 | 36.7 | 31.5 | 59.1 | 32.0 | 89.6 | 31.9 |
| Revolution Medicines Inc RVMD | 42.6 | – | -9.7 | -174,708.6 | 0.0 | -100.0 | 359.0 |
| BeiGene, Ltd. ONC | 40.8 | 64.4 | 32.4 | 88.9 | 19.1 | 40.2 | 9.1 |
| Alnylam Pharmaceuticals Inc ALNY | 34.0 | 64.4 | 28.6 | 79.7 | 23.0 | 65.2 | -45.6 |
| Royalty Pharma Plc RPRX | 32.1 | 31.4 | 19.2 | 95.8 | 100.3 | 5.1 | 70.0 |
| Median of companies shown | 42.6 | 34.3 | 19.2 | 55.0 | 20.7 | 5.1 | 37.8 |
Based on the most recently reported figures. Only stocks from the same trading venue are lined up, so the market caps are counted in one currency. Compare in a chart →
Fiscal years
Annual Figures
Fiscal years from the audited annual reports, oldest first. EBIT is the operating profit before interest and taxes; total assets are everything the company owns.
Revenue, operating income and net income per fiscal year CHF m
Revenue Operating income Net income
| Fiscal Year | Revenue (CHF m) | EBIT (CHF m) | Net Income (CHF m) | EPS (CHF) | Operating Cash Flow (CHF m) | Equity (CHF m) | Total Assets (CHF m) |
|---|---|---|---|---|---|---|---|
| 2016 | 23 | -10 | -7 | -0.14 | -6 | 142 | 156 |
| 2017 | 20 | -23 | -26 | -0.46 | -22 | 117 | 132 |
| 2018 | 7 | -50 | -51 | -0.82 | -44 | 178 | 197 |
| 2019 | 110 | 45 | 45 | 0.64 | 55 | 272 | 299 |
| 2020 | 15 | -61 | -62 | -0.86 | -60 | 215 | 239 |
| 2021 | 1 | -79 | -73 | -0.97 | -66 | 232 | 261 |
| 2022 | 4 | -71 | -71 | -0.85 | -74 | 169 | 186 |
| 2023 | 15 | -54 | -54 | -0.64 | -60 | 161 | 183 |
| 2024 | 27 | -52 | -51 | -0.51 | 66 | 112 | 231 |
| 2025 | 4 | -69 | -70 | -0.70 | -66 | 45 | 154 |
Quarters
Quarterly Figures
Each bar is one quarter, the last one is the most recent. Use the switch to step through the individual figures.
Revenue & Profit
Cash Flow
Balance Sheet
Margins
Per Share
Click the chart or tab into it, then use ← and → to step through the periods.
None of the selected stocks reports this metric. Pick another metric or switch between annual and quarterly.
· Total · per year
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The figures could not be loaded right now.
Source: fundamental data
| Quarter | EPS (Earnings Per Share) | EPS YoY (%) | Sales (CHF m) | Sales YoY (%) | Net Margin (%) | OCF (CHF m) | FCF (CHF m) |
|---|---|---|---|---|---|---|---|
| 2024: Q3 | 0.05 | 127.80 | 26 | – | 21.60 | -14 | -14 |
| 2024: Q4 | -0.16 | -220.00 | 1 | -92.30 | -1,389.40 | 6 | 6 |
| 2025: Q1 | -0.19 | -5.60 | 1 | 44.10 | -1,922.10 | -19 | -19 |
| 2025: Q2 | -0.21 | 8.70 | 1 | 90.10 | -1,622.40 | -16 | -16 |
| 2025: Q3 | -0.16 | -420.00 | 1 | -96.30 | -1,688.80 | -18 | -18 |
| 2025: Q4 | -0.14 | 12.40 | 0 | -70.30 | -4,252.40 | -16 | -17 |
| 2026: Q1 | -0.15 | 21.10 | 1 | 13.00 | -1,322.70 | – | – |
| 2026: Q2 | 0.03 | 114.30 | 15 | 1,057.20 | 12.40 | – | – |
What Do These Terms Mean?
- EPS (Earnings Per Share):
- Quarterly profit divided by the total share count — how much of the profit works out to a single share.
- YoY (Year over Year):
- Change versus the same quarter a year ago — this is how you compare without seasonal distortion (e.g. the holiday shopping season).
- Sales:
- All revenue for the quarter, before any costs are deducted — the top line of the income statement.
- Net Margin:
- What percentage of sales is left over as profit in the end. Negative means the company is posting a loss.
- OCF (Operating Cash Flow):
- The cash that actually flows into the till from the core business during the quarter — harder to dress up than book profit.
- FCF (Free Cash Flow):
- Operating cash flow minus capital expenditures — the money that's genuinely free to use, say for paying down debt, buybacks, or dividends.
Screening
Appears in These Scanners
This stock currently matches 1 of our scanner strategies — each hit links to the scanner.
Growth
Only genuine hits from verified scanners count; pure ranking metrics (P/E, P/S, and similar, which just sort the whole universe) don't count as a hit. View all scanners
Outlook
Analysts & Price Target
Combined picture of the price targets and recommendations of every analyst covering the stock. Price targets are expectations for the next 12 months, not promises — and they often follow the price rather than predict it.
Distribution of Recommendations
Estimates by Fiscal Year
| Fiscal Year | EPS Estimate (CHF) | EPS Range (CHF) | Revenue Estimate (CHF m) | Expected Growth | Analysts |
|---|---|---|---|---|---|
| 12/31/2026 | -0.41 | -0.48 – -0.35 | 19 | 41.1% | 3 |
| 12/31/2027 | 0.50 | -0.70 – 2.05 | 89 | 221.0% | 3 |
Average of the analyst estimates for the coming fiscal years. The range shows how far the most optimistic and the most cautious estimate sit apart — the wider it is, the less certain the expectation.
AI classification
AI Rating
Not yet rated — we only show a category once an SEC-backed file with at least two cited passages is available.
Growth
Growth Score
Ten checks against the annual reports — each one passed counts a point.
- Revenue grows by more than 15% a year over three years -3.2%
- More than 10% revenue growth is expected for the coming year -94.4%
- Share count grows by less than 3% a year 6.4%
- Revenue growth plus cash-flow margin add up to at least 40 ("Rule of 40") -1,962.3%
- Gross margin at 40% or higher and without meaningful erosion 100.0%
- Goodwill from acquisitions does not grow faster than revenue 0.0%
- Net debt below twice EBITDA 87 m net cash
- Operating cash flow covers the profits of the last three years 115 m
- Return on capital at 15% or higher, or up versus two years ago -115.5%
- Insiders hold at least 10% or are net buyers 37.9%
A criterion without figures counts neither as passed nor as failed; a score is only produced from 7 judgeable criteria upwards. Source: fundamental data. All ten criteria in detail
Quality check
AAQS
4/10The AAQS (AlleAktien Quality Score) checks 10 quality criteria on growth, profitability, and balance-sheet strength — per the methodology developed and published by AlleAktien, calculated by us from our own fundamental data. A stock counts as a quality stock from 9 out of 10 points. Where a company has a shorter listing history, we calculate over the fiscal years available (at least five).
- Sales growth 10Y > 5% -18.8%
- Exp. sales growth 3Y > 5% 399.9%
- EBIT growth 10Y > 5% –
- Exp. EBIT growth 3Y > 5% 399.9%
- Net debt < 4x EBIT –
- EBIT positive, 10Y straight 1
- Max. EBIT decline < 50% 100.0%
- Return on equity > 15% –
- ROCE > 15% -115.5%
- Expected return > 10% 243.1%
View stocks with the full AAQS score · Read the methodology at AlleAktien
Source: fundamental data
The company
About the Company
AC Immune SA ist ein biopharmazeutisches Unternehmen im klinischen Stadium, das Medikamente sowie therapeutische und diagnostische Produkte zur Prävention und Behandlung neurodegenerativer Erkrankungen im Zusammenhang mit Proteinfehlfaltung erforscht, entwirft und entwickelt. Die SupraAntigen- und Morphomer-Plattformen des Unternehmens sind darauf ausgelegt, Biologika und niedermolekulare Wirkstoffe zu erzeugen, die selektiv mit fehlgefalteten Proteinen interagieren, die bei einer Reihe neurodegenerativer Erkrankungen häufig vorkommen. Das Unternehmen entwickelt Crenezumab, einen humanisierten, konformationsspezifischen monoklonalen Antikörper zur Verlangsamung des Fortschreitens der Alzheimer-Krankheit (AD), sowie Semorinemab, einen experimentellen monoklonalen Anti-Tau-Antikörper, der auf den N-terminalen Teil des Tau-Proteins abzielt und darauf ausgelegt ist, an Tau zu binden und dessen Ausbreitung zwischen Neuronen zur Behandlung von AD zu verlangsamen. Das Unternehmen entwickelt zudem ACI-24.060 zur Behandlung von mit Down-Syndrom assoziiertem AD; ACI-7104.056 zur Behandlung der Parkinson-Krankheit; und ACI-35.030, das darauf ausgelegt ist, das Immunsystem eines Patienten zur Bildung von Antikörpern gegen pathologisches phosphoryliertes Tau anzuregen. Darüber hinaus entwickelt es diagnostische Programme bestehend aus PI-2620, einer Tau-Diagnostik für AD sowie für Nicht-AD-Tauopathien, sowie ACI-12589 und ACI-15916, einem Alpha-Synuclein-PET-Tracer, der die Differenzialdiagnose der Multisystematrophie gegenüber anderen neurodegenerativen Erkrankungen unterstützt. Ferner erforscht und entwickelt das Unternehmen Morphomer-Tau-Aggregationshemmer zur Bewertung von Kandidaten bei AD; Morphomer-Alpha-Synuclein zur Konkurrenz mit niedermolekularen Hemmstoffen der Alpha-Synuclein-Aggregation; sowie Programme zu NeuroOrphan-Tauopathien. Zusätzlich generiert es Moleküle im Entdeckungs- und präklinischen Stadium für eine Reihe neurodegenerativer Erkrankungen, darunter Diagnostika, die auf TDP-43, Alpha-Synuclein und NLRP3 abzielen. Das Unternehmen hat Lizenzvereinbarungen und Kooperationen mit Genentech, Inc., Janssen Pharmaceuticals, Inc., Life Molecular Imaging SA und Eli Lilly and Company. AC Immune SA wurde 2003 gegründet und hat seinen Hauptsitz in Lausanne, Schweiz.
- Employees
- 90
- Headquarters
- Lausanne, Switzerland
- Address
- Building B, 1015 Lausanne, Switzerland
- Phone
- 41 21 345 91 21
- Website
- acimmune.com
- IPO Date
- 09/23/2016
- ISIN
- CH0329023102
Management
| Name | Title | Birth Year |
|---|---|---|
| Christopher Roberts | CFO & VP of Finance | 1990 |
| Piergiorgio Donati | Chief Operating Officer | 1971 |
| Martin Zugel M.D., Ph.D. | Interim CEO & Chairman of the Board | 1963 |
| Gary Anthony Waanders Ph.D. | Senior VP of Investor Relations & Corporate Communications | 1964 |
| Matthias Maurer Ph.D. | Senior VP & General Counsel | 1982 |
| Oliver Sol M.D. | VP & Head of Clinical Development | 1968 |
| Julien Rongere Ph.D. | Senior Vice President of Regulatory Affairs & Quality Assurance | 1978 |
| Mark Danton | Executive Vice President of Information Systems & Artificial Intelligence | 1964 |
| Günther Staffler Ph.D. | Executive Vice President of Development | 1969 |
| Francesca Capotosti | Senior Vice President of Research | – |
Executives per the latest required filings; titles kept in their original language. Source: fundamental data.
Data as of: September 25, 2026 · Source: fundamental data & SEC filings (annual and quarterly reports, 10-K/10-Q)
Note: pure fact-based analysis, not investment advice and not a solicitation to buy or sell. All figures without guarantee.