Spruce Biosciences, Inc.
Ownership
Ownership Structure
Who owns Spruce Biosciences, Inc. (SPRB)? This page shows the largest institutions and funds, the ownership structure and the latest insider transactions. 70.2% of the shares are freely tradable; institutional investors hold 51.9%.
Largest Shareholders
Institutions
| Name | Stake (%) | Shares | Change (%) | Date |
|---|---|---|---|---|
| AIGH Capital Management, LLC | 8.70 | 250,000 | +0.0 | 06/30/2026 |
| Orbimed Advisors LLC | 6.96 | 200,000 | +0.0 | 06/30/2026 |
| BlackRock Inc | 6.54 | 187,836 | +1,009.0 | 06/30/2026 |
| Millennium Management LLC | 5.60 | 160,981 | +43.9 | 06/30/2026 |
| Ikarian Capital, LLC | 4.22 | 121,356 | +0.0 | 06/30/2026 |
| Vanguard Capital Management, LLC | 4.15 | 119,331 | +550.8 | 06/30/2026 |
| Alyeska Investment Group, L.P. | 2.84 | 81,671 | +58.1 | 06/30/2026 |
| Geode Capital Management, LLC | 2.45 | 70,548 | +447.4 | 06/30/2026 |
| ADAR1 Capital Management LLC | 2.36 | 67,717 | +15.6 | 06/30/2026 |
Funds
| Name | Stake (%) | Shares | Change (%) | Date |
|---|---|---|---|---|
| Vanguard MStar Total Stk Mkt Idx Invest | 2.96 | 84,935 | +0.0 | 09/30/2026 |
Largest reported positions according to regulatory filings; stake as a percentage of shares outstanding, change versus the previous filing. Source: fundamentals data.
Data as of: November 13, 2026 · Source: fundamental data & SEC filings (annual and quarterly reports, 10-K/10-Q)
Note: pure fact-based analysis, not investment advice and not a solicitation to buy or sell. All figures without guarantee.