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Buy Day today: Neutral (51) Mixed market breadth · no major macro event
IONS

Ionis Pharmaceuticals Inc

Healthcare · Biotechnology

44.40$ -4.9% vs. previous close Closing price · As of: Sep 18, 2026

Ownership

Ownership Structure

Who owns Ionis Pharmaceuticals Inc (IONS)? This page shows the largest institutions and funds, the ownership structure and the latest insider transactions. 99.2% of the shares are freely tradable; institutional investors hold 107.3%.

Institutional ownership ?Share of the stock held by institutional investors (funds, banks, insurers) according to regulatory filings. 107.3%
Insiders ?Share of the stock held by the executives, founders and major shareholders of the company itself. 0.6%
Float ?Share of stock freely tradable on the market — not locked up in the hands of founders, insiders, or major shareholders. 99.2%
Short % of float ?Shares sold short as a percentage of the freely tradable float — high values signal many bets on falling prices. 16.7%
Shares Outstanding ?Total number of shares issued. Price times share count gives market cap. 166Mio.

Largest Shareholders

Institutions

Institutions IONS
Name Stake (%) Shares Change (%) Date
FMR Inc 14.78 24,556,637 +2.0 03/31/2026
Capital World Investors 13.04 21,669,226 +2.3 06/30/2026
BlackRock Inc 6.28 10,442,476 -1.9 03/31/2026
Vanguard Portfolio Management, LLC 4.70 7,808,902 +0.0 03/31/2026
Wellington Management Company LLP 4.60 7,651,415 +19.7 06/30/2026
Vanguard Capital Management, LLC 4.28 7,118,330 +0.0 03/31/2026

Funds

Funds IONS
Name Stake (%) Shares Change (%) Date
Fidelity Growth Compy Commingled Pl S 6.78 11,275,122 +0.4 07/31/2026
Fidelity Growth Company Fund 5.12 8,503,255 +0.4 07/31/2026
Capital Group Growth Fnd of Amer Comp 4.61 7,668,655 +0.0 06/30/2026
American Funds Growth Fd of Amer A 4.61 7,668,655 +0.0 06/30/2026

Largest reported positions according to regulatory filings; stake as a percentage of shares outstanding, change versus the previous filing. Source: fundamentals data.

Insider holdings

Insider holdings IONS
Person Role Shares Value As of Type
Monia Brett P Chief Executive Officer 242,760 10,778,544 $ Aug 31, 2026 direct
Berthelsen Spencer R Director 161,233 7,158,745 $ Jul 15, 2026 direct
Birchler Brian EVP, Corp and Development Ops 102,883 4,568,005 $ Aug 31, 2026 direct
Bennett C Frank EVP, Chief Scientific Officer 60,128 2,669,683 $ Jul 7, 2026 both
O'neil Patrick R. EVP CLO & General Counsel 59,205 2,628,702 $ Aug 31, 2026 direct
Herman Joan E Director 51,306 2,277,986 $ Jul 15, 2026 direct
Hayden Michael R Director 24,000 1,065,600 $ Jul 31, 2026 indirect
Kordasiewicz Holly B. EVP, Chief Development Officer 22,096 981,062 $ Jul 7, 2026 direct
Diaz Allene M. Director 3,811 169,208 $ Jul 7, 2026 direct

Holdings as of each person's most recent SEC Form 4 filing — excluding options and RSUs, which are not shares yet. Holdings may have changed between two filings.

Insiders

Insider Transactions

Insider Transactions
Date Person Role Type Shares Price Value
Aug 31, 2026 Bennett C Frank EVP, Chief Scientific Officer Other 110 51.31 5,644
Aug 31, 2026 O'neil Patrick R. EVP CLO & General Counsel Other 63 51.31 3,232
Aug 31, 2026 Monia Brett P Chief Executive Officer Other 98 51.31 5,028
Aug 31, 2026 Birchler Brian EVP, Corp and Development Ops Other 58 51.31 2,976
Jul 31, 2026 Hayden Michael R Director Buy 5,000 51.60 258,000
Jul 30, 2026 Hayden Michael R Director Buy 15,000 53.38 800,700
Jul 15, 2026 Herman Joan E Director Other 5,220 0.00
Jul 15, 2026 Berthelsen Spencer R Director Other 5,220 0.00
Jul 7, 2026 Bennett C Frank EVP, Chief Scientific Officer Sell 15,000 85.46 1,281,930
Jul 7, 2026 Bennett C Frank EVP, Chief Scientific Officer Other 15,000 0.00
Jul 7, 2026 Bennett C Frank EVP, Chief Scientific Officer Sell 5,536 83.58 462,693
Jul 7, 2026 Diaz Allene M. Director Sell 10,111 85.42 863,637
Jul 7, 2026 Diaz Allene M. Director Other 10,111 47.11 476,329
Jul 7, 2026 Kordasiewicz Holly B. EVP, Chief Development Officer Sell 362 84.30 30,517

Reportable transactions by officers and major shareholders from SEC Form 4 filings. "Other" includes things like stock grants and option exercises without a buy/sell character. View all insider transactions →

Data as of: September 18, 2026 · Source: fundamental data & SEC filings (annual and quarterly reports, 10-K/10-Q)

Note: pure fact-based analysis, not investment advice and not a solicitation to buy or sell. All figures without guarantee.

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