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Buy Day today: Neutral (55) Mixed market breadth · no major macro event
DFTX

Definium Therapeutics, Inc.

Healthcare · Biotechnology · —

33.40$ +2.9% vs. previous close Closing price · As of: Nov 3, 2026

Ownership

Ownership Structure

Who owns Definium Therapeutics, Inc. (DFTX)? This page shows the largest institutions and funds, the ownership structure and the latest insider transactions. 93.4% of the shares are freely tradable; institutional investors hold 65.6%.

Institutional ownership ?Share of the stock held by institutional investors (funds, banks, insurers) according to regulatory filings. 65.6%
Insiders ?Share of the stock held by the executives, founders and major shareholders of the company itself. 1.2%
Float ?Share of stock freely tradable on the market — not locked up in the hands of founders, insiders, or major shareholders. 93.4%
Short % of float ?Shares sold short as a percentage of the freely tradable float — high values signal many bets on falling prices. 7.5%
Shares Outstanding ?Total number of shares issued. Price times share count gives market cap. 134Mio.

Largest Shareholders

Institutions

Institutions DFTX
Name Stake (%) Shares Change (%) Date
BlackRock Inc 8.36 11,232,834 +32.5 06/30/2026
venBio Select Advisor LLC 5.35 7,188,888 +43.8 06/30/2026
Driehaus Capital Management LLC 5.09 6,845,276 +15.8 06/30/2026
Jupiter Topco LLC 4.18 5,615,645 +0.0 06/30/2026
Capital World Investors 3.99 5,367,723 +0.0 06/30/2026
FMR Inc 3.54 4,752,921 +162.6 06/30/2026
T. Rowe Price Associates, Inc. 3.46 4,652,032 +6,545.7 06/30/2026
Geode Capital Management, LLC 2.71 3,644,813 +46.1 06/30/2026
HHG PLC 2.65 3,556,041 +47.4 03/31/2026

Funds

Funds DFTX
Name Stake (%) Shares Change (%) Date
American Funds SMALLCAP World A 7.63 10,253,153 +33.3 09/30/2026

Largest reported positions according to regulatory filings; stake as a percentage of shares outstanding, change versus the previous filing. Source: fundamentals data.

Insider holdings

Insider holdings DFTX
Person Role Shares Value As of Type
Barrow Robert Chief Executive Officer 2,213,090 73,917,206 $ Sep 25, 2026 direct
Karlin Daniel Chief Medical Officer 792,846 26,481,056 $ Sep 25, 2026 direct
Sullivan Mark Chief Legal Officer 494,228 16,507,215 $ Sep 25, 2026 direct
Roberts Brandi Chief Financial Officer 394,528 13,177,235 $ Sep 25, 2026 direct
Wiley Matthew T. Chief Commercial Officer 359,036 11,991,802 $ Sep 25, 2026 direct
Vallone Carol A Director 22,296 744,686 $ Sep 18, 2026 direct
Krebs Andreas Director 21,402 714,827 $ Sep 18, 2026 direct

Holdings as of each person's most recent SEC Form 4 filing — excluding options and RSUs, which are not shares yet. Holdings may have changed between two filings.

Insiders

Insider Transactions

Insider Transactions
Date Person Role Type Shares Price Value
Sep 25, 2026 Karlin Daniel Chief Medical Officer Sell 10,853 36.57 396,894
Sep 25, 2026 Barrow Robert Chief Executive Officer Sell 31,550 36.57 1,153,784
Sep 25, 2026 Wiley Matthew T. Chief Commercial Officer Sell 3,097 36.57 113,257
Sep 25, 2026 Sullivan Mark Chief Legal Officer Sell 14,051 36.57 513,845
Sep 25, 2026 Roberts Brandi Chief Financial Officer Sell 3,377 36.57 123,497
Sep 18, 2026 Krebs Andreas Director Other 1,629 35.52 57,862
Sep 18, 2026 Vallone Carol A Director Other 1,086 35.52 38,575
Sep 14, 2026 Karlin Daniel Chief Medical Officer Other 200,000 0.00 –
Sep 14, 2026 Wiley Matthew T. Chief Commercial Officer Other 125,000 0.00 –
Sep 14, 2026 Sullivan Mark Chief Legal Officer Other 125,000 0.00 –
Sep 14, 2026 Roberts Brandi Chief Financial Officer Other 125,000 0.00 –
Sep 14, 2026 Barrow Robert Chief Executive Officer Other 750,000 0.00 –
Sep 3, 2026 Barrow Robert Chief Executive Officer Sell 19,023 37.94 721,733
Sep 2, 2026 Barrow Robert Chief Executive Officer Other 40,000 0.00 –
Aug 12, 2026 Barrow Robert Chief Executive Officer Other 375,000 0.00 –
Aug 12, 2026 Karlin Daniel Chief Medical Officer Other 100,000 0.00 –
Aug 12, 2026 Sullivan Mark Chief Legal Officer Other 62,500 0.00 –
Aug 12, 2026 Wiley Matthew T. Chief Commercial Officer Other 62,500 0.00 –
Aug 12, 2026 Roberts Brandi Chief Financial Officer Other 62,500 0.00 –

Reportable transactions by officers and major shareholders from SEC Form 4 filings. "Other" includes things like stock grants and option exercises without a buy/sell character. View all insider transactions →

Data as of: November 3, 2026 · Source: fundamental data & SEC filings (annual and quarterly reports, 10-K/10-Q)

Note: pure fact-based analysis, not investment advice and not a solicitation to buy or sell. All figures without guarantee.

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