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Buy Day today: Neutral (51) Mixed market breadth · no major macro event

Insider Trading

Current insider transactions (SEC Form 4) — buys and sells by officers, directors, and major shareholders.

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A compact market overview — not investment advice. Source: fundamental data & SEC filings (annual and quarterly reports, 10-K/10-Q).
Ticker Insider Title Date Transaction Price ($) Shares Value ($) SEC Form 4
ORKA Goncalves Joana Chief Medical Officer 09/15/2026 Verkauf 95.71 947 90,637 Form 4
ORKA Goncalves Joana Chief Medical Officer 09/15/2026 Verkauf 94.22 100 9,422 Form 4
ORKA Goncalves Joana Chief Medical Officer 09/15/2026 Verkauf 92.99 1,366 127,023 Form 4
ORKA Goncalves Joana Chief Medical Officer 09/15/2026 Verkauf 92.03 3,150 289,890 Form 4
ORKA Goncalves Joana Chief Medical Officer 09/15/2026 Verkauf 91.10 2,384 217,173 Form 4
ORKA Goncalves Joana Chief Medical Officer 09/15/2026 Optionsausübung 7.80 3,500 27,300 Form 4
ORKA Agarwal Arjun Senior Vice President, Finance 09/15/2026 Verkauf 95.71 560 53,598 Form 4
ORKA Klein Lawrence Otto Chief Executive Officer 09/15/2026 Verkauf 95.71 2,452 234,681 Form 4
ORKA Quinlan Paul T General Counsel 09/15/2026 Verkauf 95.71 1,039 99,443 Form 4
ORKA Sandler Laura Lee Chief Operating Officer 09/15/2026 Verkauf 95.71 906 86,713 Form 4
ORKA Agarwal Arjun Senior Vice President, Finance 09/11/2026 Verkauf 94.02 200 18,803 Form 4
ORKA Agarwal Arjun Senior Vice President, Finance 09/11/2026 Verkauf 93.26 2,208 205,921 Form 4
ORKA Agarwal Arjun Senior Vice President, Finance 09/11/2026 Verkauf 92.41 4,051 374,367 Form 4
ORKA Agarwal Arjun Senior Vice President, Finance 09/11/2026 Verkauf 91.11 3,000 273,322 Form 4
ORKA Agarwal Arjun Senior Vice President, Finance 09/11/2026 Optionsausübung 34.39 1,459 50,175 Form 4
ORKA Agarwal Arjun Senior Vice President, Finance 09/11/2026 Optionsausübung 12.50 8,000 100,000 Form 4
ORKA Sandler Laura Lee Chief Operating Officer 09/01/2026 Verkauf 92.01 4,000 368,054 Form 4
ORKA Sandler Laura Lee Chief Operating Officer 09/01/2026 Verkauf 91.05 1,000 91,048 Form 4
ORKA Sandler Laura Lee Chief Operating Officer 09/01/2026 Optionsausübung 7.80 5,000 39,000 Form 4
ORKA Klein Lawrence Otto Chief Executive Officer 09/01/2026 Verkauf 92.44 4,800 443,691 Form 4
ORKA Klein Lawrence Otto Chief Executive Officer 09/01/2026 Verkauf 91.90 63,596 5,844,237 Form 4
ORKA Klein Lawrence Otto Chief Executive Officer 09/01/2026 Verkauf 90.79 6,604 599,556 Form 4
ORKA Klein Lawrence Otto Chief Executive Officer 09/01/2026 Optionsausübung 7.80 75,000 585,000 Form 4
ORKA Edwards Larry Todd Chief Commercial Officer 08/24/2026 Zuteilung 100,000 Form 4
ORKA Goncalves Joana Chief Medical Officer 08/17/2026 Verkauf 112.56 2,480 279,154 Form 4
ORKA Goncalves Joana Chief Medical Officer 08/17/2026 Verkauf 112.01 3,320 371,886 Form 4
ORKA Goncalves Joana Chief Medical Officer 08/17/2026 Verkauf 110.52 300 33,155 Form 4
ORKA Goncalves Joana Chief Medical Officer 08/17/2026 Verkauf 109.65 900 98,687 Form 4
ORKA Goncalves Joana Chief Medical Officer 08/17/2026 Optionsausübung 7.80 3,500 27,300 Form 4
ORKA Quinlan Paul T General Counsel 08/14/2026 Verkauf 111.14 3,847 427,547 Form 4
ORKA Quinlan Paul T General Counsel 08/14/2026 Verkauf 110.00 9,193 1,011,266 Form 4
ORKA Quinlan Paul T General Counsel 08/14/2026 Verkauf 109.11 10,200 1,112,954 Form 4
ORKA Quinlan Paul T General Counsel 08/14/2026 Verkauf 107.97 14,696 1,586,779 Form 4
ORKA Quinlan Paul T General Counsel 08/14/2026 Verkauf 107.14 10,434 1,117,901 Form 4
ORKA Quinlan Paul T General Counsel 08/14/2026 Verkauf 106.05 3,630 384,963 Form 4
ORKA Quinlan Paul T General Counsel 08/14/2026 Optionsausübung 12.50 42,000 525,000 Form 4
ORKA Quinlan Paul T General Counsel 08/14/2026 Optionsausübung 7.80 10,000 78,000 Form 4
ORKA Agarwal Arjun Senior Vice President, Finance 08/13/2026 Verkauf 108.46 2,358 255,755 Form 4
ORKA Agarwal Arjun Senior Vice President, Finance 08/13/2026 Verkauf 107.71 2,142 230,723 Form 4
ORKA Agarwal Arjun Senior Vice President, Finance 08/13/2026 Verkauf 106.63 1,268 135,201 Form 4
ORKA Agarwal Arjun Senior Vice President, Finance 08/13/2026 Verkauf 105.57 2,132 225,079 Form 4
ORKA Agarwal Arjun Senior Vice President, Finance 08/13/2026 Verkauf 104.67 2,100 219,814 Form 4
ORKA Agarwal Arjun Senior Vice President, Finance 08/13/2026 Optionsausübung 34.39 1,458 50,141 Form 4
ORKA Agarwal Arjun Senior Vice President, Finance 08/13/2026 Optionsausübung 12.50 8,542 106,775 Form 4
ORKA Goncalves Joana Chief Medical Officer 07/15/2026 Verkauf 87.25 300 26,176 Form 4
ORKA Goncalves Joana Chief Medical Officer 07/15/2026 Verkauf 86.68 3,803 329,630 Form 4
ORKA Goncalves Joana Chief Medical Officer 07/15/2026 Verkauf 85.86 2,497 214,385 Form 4
ORKA Goncalves Joana Chief Medical Officer 07/15/2026 Verkauf 84.37 400 33,746 Form 4
ORKA Goncalves Joana Chief Medical Officer 07/15/2026 Optionsausübung 7.80 3,500 27,300 Form 4
ORKA Agarwal Arjun Senior Vice President, Finance 07/13/2026 Verkauf 84.90 5,656 480,201 Form 4
ORKA Agarwal Arjun Senior Vice President, Finance 07/13/2026 Verkauf 84.26 3,743 315,369 Form 4
ORKA Agarwal Arjun Senior Vice President, Finance 07/13/2026 Verkauf 85.63 300 25,690 Form 4
ORKA Agarwal Arjun Senior Vice President, Finance 07/13/2026 Optionsausübung 34.39 1,458 50,141 Form 4
ORKA Agarwal Arjun Senior Vice President, Finance 07/13/2026 Optionsausübung 12.50 8,541 106,763 Form 4

A compact market overview — not investment advice. Source: fundamental data & SEC filings (annual and quarterly reports, 10-K/10-Q).

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