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Buy Day today: Neutral (58) Mixed market breadth · major macro event coming up

Insider Trading

Current insider transactions (SEC Form 4) — buys and sells by officers, directors, and major shareholders.

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A compact market overview — not investment advice. Source: fundamental data & SEC filings (annual and quarterly reports, 10-K/10-Q).
Ticker Insider Title Date Transaction Price ($) Shares Value ($) SEC Form 4
ORKA Klein Lawrence Otto Chief Executive Officer 11/02/2026 Verkauf 98.40 300 29,521 Form 4
ORKA Klein Lawrence Otto Chief Executive Officer 11/02/2026 Verkauf 97.45 756 73,676 Form 4
ORKA Klein Lawrence Otto Chief Executive Officer 11/02/2026 Verkauf 96.70 2,442 236,147 Form 4
ORKA Klein Lawrence Otto Chief Executive Officer 11/02/2026 Verkauf 95.64 15,036 1,437,987 Form 4
ORKA Klein Lawrence Otto Chief Executive Officer 11/02/2026 Verkauf 94.77 6,466 612,794 Form 4
ORKA Klein Lawrence Otto Chief Executive Officer 11/02/2026 Optionsausübung 7.80 25,000 195,000 Form 4
ORKA Quinlan Paul T General Counsel 10/20/2026 Verkauf 79.49 3,000 238,474 Form 4
ORKA Quinlan Paul T General Counsel 10/20/2026 Verkauf 78.79 4,100 323,037 Form 4
ORKA Quinlan Paul T General Counsel 10/20/2026 Verkauf 77.21 1,000 77,205 Form 4
ORKA Quinlan Paul T General Counsel 10/20/2026 Verkauf 76.12 500 38,059 Form 4
ORKA Quinlan Paul T General Counsel 10/20/2026 Verkauf 74.90 400 29,960 Form 4
ORKA Quinlan Paul T General Counsel 10/20/2026 Optionsausübung 7.80 9,000 70,200 Form 4
ORKA Goncalves Joana Chief Medical Officer 10/15/2026 Verkauf 77.71 200 15,542 Form 4
ORKA Goncalves Joana Chief Medical Officer 10/15/2026 Verkauf 76.67 700 53,666 Form 4
ORKA Goncalves Joana Chief Medical Officer 10/15/2026 Verkauf 75.48 1,400 105,677 Form 4
ORKA Goncalves Joana Chief Medical Officer 10/15/2026 Verkauf 74.69 1,847 137,957 Form 4
ORKA Goncalves Joana Chief Medical Officer 10/15/2026 Verkauf 73.89 2,853 210,806 Form 4
ORKA Goncalves Joana Chief Medical Officer 10/15/2026 Optionsausübung 7.80 3,500 27,300 Form 4
ORKA Agarwal Arjun Senior Vice President, Finance 10/12/2026 Verkauf 82.84 200 16,567 Form 4
ORKA Agarwal Arjun Senior Vice President, Finance 10/12/2026 Verkauf 81.86 1,958 160,272 Form 4
ORKA Agarwal Arjun Senior Vice President, Finance 10/12/2026 Verkauf 80.76 2,100 169,596 Form 4
ORKA Agarwal Arjun Senior Vice President, Finance 10/12/2026 Verkauf 80.03 5,741 459,453 Form 4
ORKA Agarwal Arjun Senior Vice President, Finance 10/12/2026 Optionsausübung 34.39 1,458 50,141 Form 4
ORKA Agarwal Arjun Senior Vice President, Finance 10/12/2026 Optionsausübung 12.50 8,541 106,763 Form 4
ORKA Klein Lawrence Otto Chief Executive Officer 10/01/2026 Verkauf 84.78 200 16,956 Form 4
ORKA Klein Lawrence Otto Chief Executive Officer 10/01/2026 Verkauf 84.03 8,554 718,755 Form 4
ORKA Klein Lawrence Otto Chief Executive Officer 10/01/2026 Verkauf 83.40 16,246 1,354,882 Form 4
ORKA Klein Lawrence Otto Chief Executive Officer 10/01/2026 Optionsausübung 7.80 25,000 195,000 Form 4
ORKA Agarwal Arjun Senior Vice President, Finance 09/21/2026 Verkauf 95.75 533 51,035 Form 4
ORKA Quinlan Paul T General Counsel 09/21/2026 Verkauf 95.31 2,667 254,196 Form 4
ORKA Quinlan Paul T General Counsel 09/21/2026 Verkauf 94.44 601 56,760 Form 4
ORKA Quinlan Paul T General Counsel 09/21/2026 Verkauf 93.32 3,832 357,592 Form 4
ORKA Quinlan Paul T General Counsel 09/21/2026 Verkauf 92.37 2,900 267,870 Form 4
ORKA Quinlan Paul T General Counsel 09/21/2026 Optionsausübung 7.80 10,000 78,000 Form 4
ORKA Goncalves Joana Chief Medical Officer 09/15/2026 Verkauf 95.71 947 90,637 Form 4
ORKA Goncalves Joana Chief Medical Officer 09/15/2026 Verkauf 94.22 100 9,422 Form 4
ORKA Goncalves Joana Chief Medical Officer 09/15/2026 Verkauf 92.99 1,366 127,023 Form 4
ORKA Goncalves Joana Chief Medical Officer 09/15/2026 Verkauf 92.03 3,150 289,890 Form 4
ORKA Goncalves Joana Chief Medical Officer 09/15/2026 Verkauf 91.10 2,384 217,173 Form 4
ORKA Goncalves Joana Chief Medical Officer 09/15/2026 Optionsausübung 7.80 3,500 27,300 Form 4
ORKA Agarwal Arjun Senior Vice President, Finance 09/15/2026 Verkauf 95.71 560 53,598 Form 4
ORKA Klein Lawrence Otto Chief Executive Officer 09/15/2026 Verkauf 95.71 2,452 234,681 Form 4
ORKA Quinlan Paul T General Counsel 09/15/2026 Verkauf 95.71 1,039 99,443 Form 4
ORKA Sandler Laura Lee Chief Operating Officer 09/15/2026 Verkauf 95.71 906 86,713 Form 4
ORKA Agarwal Arjun Senior Vice President, Finance 09/11/2026 Verkauf 94.02 200 18,803 Form 4
ORKA Agarwal Arjun Senior Vice President, Finance 09/11/2026 Verkauf 93.26 2,208 205,921 Form 4
ORKA Agarwal Arjun Senior Vice President, Finance 09/11/2026 Verkauf 92.41 4,051 374,367 Form 4
ORKA Agarwal Arjun Senior Vice President, Finance 09/11/2026 Verkauf 91.11 3,000 273,322 Form 4
ORKA Agarwal Arjun Senior Vice President, Finance 09/11/2026 Optionsausübung 34.39 1,459 50,175 Form 4
ORKA Agarwal Arjun Senior Vice President, Finance 09/11/2026 Optionsausübung 12.50 8,000 100,000 Form 4
ORKA Sandler Laura Lee Chief Operating Officer 09/01/2026 Verkauf 92.01 4,000 368,054 Form 4
ORKA Sandler Laura Lee Chief Operating Officer 09/01/2026 Verkauf 91.05 1,000 91,048 Form 4
ORKA Sandler Laura Lee Chief Operating Officer 09/01/2026 Optionsausübung 7.80 5,000 39,000 Form 4
ORKA Klein Lawrence Otto Chief Executive Officer 09/01/2026 Verkauf 92.44 4,800 443,691 Form 4
ORKA Klein Lawrence Otto Chief Executive Officer 09/01/2026 Verkauf 91.90 63,596 5,844,237 Form 4
ORKA Klein Lawrence Otto Chief Executive Officer 09/01/2026 Verkauf 90.79 6,604 599,556 Form 4
ORKA Klein Lawrence Otto Chief Executive Officer 09/01/2026 Optionsausübung 7.80 75,000 585,000 Form 4
ORKA Edwards Larry Todd Chief Commercial Officer 08/24/2026 Zuteilung — 100,000 — Form 4
ORKA Goncalves Joana Chief Medical Officer 08/17/2026 Verkauf 112.56 2,480 279,154 Form 4
ORKA Goncalves Joana Chief Medical Officer 08/17/2026 Verkauf 112.01 3,320 371,886 Form 4

A compact market overview — not investment advice. Source: fundamental data & SEC filings (annual and quarterly reports, 10-K/10-Q).

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