SPRO
Spero Therapeutics Inc
1.20$
-2.5%
vs. previous close
Closing price · As of: Oct 5, 2026
Statements
Ratios
Valuation ratios (P/E, P/S, EV/EBITDA and the other multiples) are based on the closing price at the end of each period, not on the current price. Margins and returns are shown in percent, multiples without a unit, per-share figures in the reporting currency, net debt in millions.
Tick rows to compare them in a chart (up to 4)
| Line item | Q3 16 | Q4 16 | Q1 17 | Q2 17 | Q3 17 | Q4 17 | Q1 18 | Q2 18 | Q3 18 | Q4 18 | Q1 19 | Q2 19 | Q3 19 | Q4 19 | Q1 20 | Q2 20 | Q3 20 | Q4 20 | Q1 21 | Q2 21 | Q3 21 | Q4 21 | Q1 22 | Q2 22 | Q3 22 | Q4 22 | Q1 23 | Q2 23 | Q3 23 | Q4 23 | Q1 24 | Q2 24 | Q3 24 | Q4 24 | Q1 25 | Q2 25 | Q3 25 | Q4 25 | Q1 26 | Q2 26 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Valuation | ||||||||||||||||||||||||||||||||||||||||
| – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | 3.5 | 3.9 | 4.0 | 20.0 | – | – | – | – | 15.9 | 8.6 | 17.3 | |
| – | – | – | – | – | 99.9 | 79.2 | 75.2 | 63.9 | 27.7 | 33.3 | 24.4 | 25.3 | 18.7 | 20.7 | 38.5 | 22.2 | 56.9 | 29.0 | 27.1 | 49.2 | 40.0 | 48.9 | 5.3 | 14.4 | 1.7 | 1.6 | 1.5 | 0.8 | 0.8 | 0.9 | 0.6 | 0.7 | 1.3 | 0.9 | 3.5 | 3.0 | 2.3 | 2.4 | 3.0 | |
| – | – | – | – | – | 1.9 | 2.8 | 3.2 | 1.5 | 0.9 | 2.0 | 1.9 | 2.1 | 2.5 | 1.9 | 3.8 | 1.9 | 4.0 | 3.6 | 4.6 | 5.3 | 5.8 | 4.5 | 0.7 | 2.2 | 1.1 | 1.2 | 1.4 | 1.2 | 0.7 | 0.9 | 0.9 | 1.1 | 1.2 | 1.2 | 4.9 | 4.0 | 2.3 | 2.5 | 2.9 | |
| – | – | – | – | – | 84.0 | 59.0 | 58.0 | 49.9 | 19.2 | 26.6 | 16.0 | 19.5 | 15.8 | 12.4 | 29.6 | 11.0 | 47.9 | 23.9 | 22.5 | 39.9 | 31.3 | 45.5 | -4.2 | 4.7 | -0.5 | -0.3 | 0.1 | -0.4 | 0.0 | 0.1 | 0.1 | 0.0 | 0.1 | -0.2 | 2.9 | 1.7 | 1.6 | 1.4 | 1.8 | |
| – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | -5.3 | 0.2 | 0.3 | 0.3 | -1.1 | – | – | – | – | 13.0 | 5.2 | 10.2 | |
| – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | 10.5 | 6.6 | 2.2 | – | – | – | – | – | – | – | – | – | 18.2 | 6.5 | |
| – | – | – | – | – | -23.3% | -20.4% | -19.7% | -20.0% | -38.2% | -18.6% | -22.0% | -24.7% | -27.5% | -39.6% | -27.1% | -35.5% | -16.2% | -18.1% | -16.8% | -9.0% | -12.5% | -27.2% | -341.9% | -110.9% | -9.5% | 9.5% | 15.2% | 45.6% | -41.4% | -15.6% | -20.5% | -24.9% | -43.4% | -83.7% | -19.9% | -25.9% | -9.2% | 5.5% | 15.4% | |
| Margins | ||||||||||||||||||||||||||||||||||||||||
| – | -3,220.9% | 100.0% | 100.0% | 100.0% | -1,506.7% | -879.7% | -805.1% | -785.9% | 100.0% | 100.0% | 100.0% | 100.0% | -163.5% | -502.7% | -538.5% | -477.9% | -308.8% | -141.9% | -135.9% | -53.1% | -177.1% | -196.7% | -274.9% | -246.6% | 100.0% | 82.2% | 64.6% | 75.1% | 34.0% | 43.8% | 34.9% | 27.8% | -175.8% | -196.0% | -134.3% | -202.6% | 77.5% | 100.0% | – | |
| – | -8,970.4% | -5,120.6% | -4,763.5% | -2,766.1% | -2,381.3% | -1,576.0% | -1,449.1% | -1,452.0% | -1,079.3% | -569.3% | -497.6% | -618.6% | -647.4% | -1,049.0% | -1,177.9% | -779.9% | -847.9% | -507.0% | -494.9% | -659.4% | -684.2% | -1,701.6% | -2,313.7% | -1,924.4% | -86.9% | -52.0% | -24.9% | -4.1% | 20.7% | 20.5% | 13.7% | -1.1% | -170.9% | -166.2% | -124.5% | -130.9% | 10.5% | 24.7% | 14.0% | |
| – | -7,069.0% | -4,084.8% | -3,946.4% | -2,429.4% | -2,193.1% | -1,521.0% | -1,433.2% | -1,424.6% | -1,050.5% | -545.2% | -472.6% | -594.6% | -623.9% | -1,032.9% | -1,154.4% | -766.1% | -839.0% | -498.7% | -493.3% | -658.0% | -698.1% | -1,777.1% | -2,465.1% | -2,061.3% | -95.5% | -53.3% | -19.3% | -2.1% | 22.0% | 22.1% | 15.4% | 3.5% | -159.8% | -156.5% | -116.0% | -122.6% | 14.2% | 27.8% | 17.2% | |
| – | – | – | -4,428.3% | -2,712.8% | -2,330.1% | -1,612.8% | -1,481.6% | -1,275.9% | -1,060.0% | -620.6% | -536.5% | -623.0% | -515.5% | -819.1% | -1,044.1% | -788.3% | -922.1% | -523.1% | -455.7% | -444.2% | -500.4% | -1,328.0% | -1,818.4% | -1,601.2% | -16.2% | 14.9% | 22.9% | 37.7% | -31.8% | -13.4% | -12.7% | -17.3% | -54.6% | -74.9% | -70.0% | -77.4% | -20.9% | 13.2% | 45.6% | |
| Returns | ||||||||||||||||||||||||||||||||||||||||
| – | -232.9% | – | -89.9% | -134.2% | -41.0% | -53.0% | -61.7% | -32.7% | -36.0% | -31.9% | -35.9% | -50.2% | -81.7% | -96.0% | -113.2% | -63.8% | -59.3% | -62.6% | -83.7% | -70.7% | -101.7% | -165.1% | -315.3% | -315.3% | -61.1% | -41.4% | -18.4% | -3.0% | 21.3% | 24.3% | 21.7% | 5.4% | -148.7% | -206.3% | -163.3% | -165.5% | 14.5% | 28.8% | 16.7% | |
| – | -172.0% | -48.4% | -71.3% | -101.7% | -110.0% | -48.7% | -55.5% | -30.0% | -32.3% | -29.0% | -32.1% | -41.4% | -57.4% | -72.0% | -85.6% | -53.9% | -51.0% | -51.9% | -63.1% | -54.7% | -52.5% | -70.7% | -178.0% | -158.9% | -37.2% | -23.9% | -10.2% | -1.5% | 12.5% | 14.0% | 11.6% | 2.6% | -62.0% | -89.8% | -86.3% | -80.9% | 12.4% | 25.8% | 14.0% | |
| Balance Sheet & Debt | ||||||||||||||||||||||||||||||||||||||||
| – | – | – | – | -25 | -25 | -52 | -48 | -40 | -34 | -44 | -70 | -45 | -29 | -63 | -64 | -124 | -84 | -76 | -70 | -112 | -111 | -20 | -44 | -49 | -107 | -94 | -76 | -92 | -75 | -81 | -62 | -75 | -51 | -47 | -29 | -47 | -38 | -54 | -49 | |
| – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | -17.0 | -2.5 | -2.6 | -2.5 | -20.4 | – | – | – | – | -5.1 | -3.6 | -6.3 | |
| – | 73.8% | -93.6% | 79.3% | 75.8% | 268.2% | 92.0% | 90.0% | 92.0% | 89.8% | 90.6% | 89.2% | 82.4% | 70.3% | 75.0% | 75.6% | 84.6% | 86.0% | 82.9% | 75.5% | 77.3% | 51.6% | 42.8% | 56.5% | 50.4% | 60.8% | 57.6% | 55.4% | 50.1% | 58.6% | 57.4% | 53.7% | 48.5% | 41.7% | 43.5% | 52.8% | 48.9% | 85.6% | 89.7% | 83.8% | |
| – | – | – | – | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.8 | 0.0 | 0.1 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.1 | 0.1 | 0.1 | 0.0 | 0.0 | 0.0 | |
| Per Share | ||||||||||||||||||||||||||||||||||||||||
| – | -3.59 | -2.94 | -4.33 | -2.40 | -2.59 | -2.75 | -2.80 | -2.34 | -2.35 | -2.10 | -2.22 | -2.49 | -3.20 | -4.05 | -4.04 | -3.86 | -2.86 | -2.53 | -2.54 | -2.46 | -2.79 | -3.16 | -3.43 | -2.85 | -0.95 | -0.51 | -0.19 | -0.03 | 0.43 | 0.44 | 0.32 | 0.06 | -1.27 | -1.26 | -0.96 | -0.78 | 0.14 | 0.27 | 0.13 | |
| – | 0.05 | 0.07 | 0.11 | 0.10 | 0.12 | 0.18 | 0.20 | 0.16 | 0.22 | 0.38 | 0.47 | 0.42 | 0.51 | 0.39 | 0.35 | 0.50 | 0.34 | 0.51 | 0.52 | 0.37 | 0.40 | 0.18 | 0.14 | 0.14 | 1.00 | 0.96 | 0.99 | 1.45 | 1.95 | 1.98 | 2.10 | 1.87 | 0.79 | 0.81 | 0.82 | 0.64 | 1.02 | 0.96 | 0.74 | |
| – | 1.54 | -5.68 | 4.81 | 1.79 | 6.31 | 5.19 | 4.54 | 7.17 | 6.53 | 6.56 | 6.19 | 4.97 | 3.91 | 4.21 | 3.57 | 6.05 | 4.82 | 4.04 | 3.04 | 3.48 | 2.75 | 1.92 | 1.09 | 0.91 | 1.56 | 1.23 | 1.04 | 1.02 | 2.01 | 1.80 | 1.49 | 1.21 | 0.85 | 0.61 | 0.59 | 0.47 | 0.99 | 0.92 | 0.76 | |
| – | – | – | -4.85 | -2.67 | -2.75 | -2.91 | -2.90 | -2.10 | -2.37 | -2.39 | -2.52 | -2.61 | -2.64 | -3.21 | -3.66 | -3.97 | -3.14 | -2.66 | -2.35 | -1.66 | -2.00 | -2.36 | -2.53 | -2.22 | -0.16 | 0.14 | 0.23 | 0.55 | -0.62 | -0.27 | -0.27 | -0.32 | -0.43 | -0.60 | -0.58 | -0.49 | -0.21 | 0.13 | 0.34 | |
Showing the most recent 40 periods — older statements are on file for this stock.
Data as of: October 5, 2026 · Source: fundamental data & SEC filings (annual and quarterly reports, 10-K/10-Q)
Note: pure fact-based analysis, not investment advice and not a solicitation to buy or sell. All figures without guarantee.